Dexalgin tablets: instructions for use. Dexalgin - instructions from packaging and release form, warehouse, indicated price Dexalgin 20 injections

Zmist

The medication Dexalgin is a non-steroidal anti-inflammatory drug that is used to relieve pain, relieve heat and inflammation. This complex of drugs contains the active substance trometamol dexketoprofen. Please familiarize yourself with the instructions according to the instructions.

Warehouse and form

Dexalgin is available in three formats: tablets, oral granules and injections. Warehouse and packaging features:

			Pigulki
Description	Zhovti granules with lemon taste and aroma	Prozora is ridin with the smell of alcohol	White round tablets
Concentration of dexketoprofen, mg	25 for 1 sachet	25 per 1 ml (50 per 1 ampoule)
Additional components	Silicon dioxide, ammonium glycyrrizate, sucrose, neohesperidine dihydrochalcone, lemon flavor, yellow quinoline	Sodium hydroxide, ethanol, water, sodium chloride	Propylene glycol, microcrystalline cellulose, macrogol, corn starch, titanium dioxide, sodium carboxymethyl starch, hypromellose, palmitostearate, glycerin, glycerin
Package	10 or 30 sachets per box with instructions for freezing	Ampoules of 2 ml, 1, 5 or 10 ampoules per pack	Blisters of 10 pcs., 1, 3 or 5 blisters per box

Pharmacodynamics and pharmacokinetics

The non-steroidal anti-inflammatory drug has an antipyretic, analgesic effect, which is associated with suppressed production of prostaglandins and cyclooxygenase enzymes, which are responsible for inflammation. The pain effect begins within a few years of drying out of the skin and lasts up to eight years. When Dexalgin is taken simultaneously with opioid analgesics, their requirement decreases by 45%.

After intralingual administration, dexketoprofen reaches a maximum concentration after 20 weeks, and when administered orally, after a day. The drug binds to plasma proteins by 99%, is eliminated in the body (indicates metabolism) and conjugates (binds) with glucuronic acid. Metabolites are excreted by nitric acid, the recovery period is 1-2.5 years. In the summer, the hour for the drug to be eliminated from the body increases.

Showing before stagnation

The instructions for administration of Dexalgin indicate its indication before use. It is clear to them:

pain after surgery, dental pain, menstrual pain;
radiculitis, algodismenorrhea;
neuralgia, ischialgia, arthrosis;
rheumatoid arthritis, spondyloarthritis, cyst metastases, osteochondrosis;
pain syndrome after injuries, narcotic injections;
acute and chronic inflammation and degenerative metabolic illnesses.

Method of curing and dosing

Instructions for taking Dexalgin should be placed in the release form of the medication. Thus, the granules are intended for oral administration. The average single dose is 12.5 mg daily for 4-6 years per dose (1-6 times per day) or 25 mg daily for 8 years (three times per dose). The maximum dose of granules is 75 mg, the course lasts 3-5 days. If the patient's liver function is impaired or poor, the daily dose should not exceed 50 mg per dose.

Dexalgin injections

For instructions, Dexalgin in ampoules is administered internally or internally. The dose has increased to 50 mg per day for 8-12 years, but not more than 150 mg per dose. The procedure can be introduced at a six-year interval. In summer, in case of liver failure, or at any time, the required dose is 50 mg. Ampoules cannot be frozen for more than two days after treatment for the treatment of acute pain syndrome, otherwise the patient must be transferred to taking tablets or granules.

Instead of one ampoules, you can administer it deeply internally, completely (15 seconds) internally, as an infusion, which lasts 10-30 minutes. For the other method, dilute 2 ml of the drug with 30-100 ml of physiological, glucose or lactate (Ringer) doses. Sumish is preparing in the minds of asepsis under the protection of the infusion of sunny light. The effectiveness of the drug depends on the method of administration.

The average recommended dosing instructions for tablets is 12.5 mg 1-6 times per dose (skin 4-6 years, half a piece) or 25 mg (1 piece) 1-3 times a day at intervals of every year. The maximum dose of Likiv is 3 tablets or 75 mg. If the patient has impaired functioning of the liver, liver, or in the summer, then the initial dosage of tablets is no more than 50 mg per dose. The treatment course lasts 3-5 days.

special inserts

Patients with impaired functioning of the herbal system require constant control. If there is a suspicion of infection or bleeding, therapy with the drug is canceled. Other special inserts with instructions for freezing:

Dexalgin may have side effects on the thyroid system and lead to the development of nephrotic syndrome.
Against the background of treatment with the drug, the activity of liver enzymes may increase.
Make sure to mask the symptoms of infection.
The medication may cause drowsiness and confusion, so during the course of therapy it is easier to cope with the procedure using transport and mechanisms.

Medical mutualism

The use of Dexalgin is associated with a low incidence of serious symptoms, which may occur when used with other people. The instructions describe the following combination and effects:

When combined with other non-steroidal anti-inflammatory drugs, high doses of salicylates lead to an increased risk of scutulo-intestinal bleeding and bleeding, as a result of which a synergism of action is manifested.
Combinations of dexketoprofen with Heparin, Ticlopidine, oral anticoagulants, Pentoxifyline, thrombolytics, Sertraline, Theophylline, Fluoxetine, Quinolone, Citalopram can increase the chance of developing bleeding.
The drug increases the concentration of lithium in the blood plasma, even to the point of toxicity, enhancing the toxicity of sulfonamides and hydantoins.
Increased hematological toxicity of Methotrexate and Heparin decreases their nitric clearance.
The combination of the drug with zidovudine can lead to toxic effects on red blood cells, severe anemia, and lipid effects on reticulocytes.
The use of diuretics can lead to fever and acute nicotine deficiency.
Dexketoprofen enhances the hypoglycemic effect of drugs based on sulfonyl compounds.
Probenecid increases the plasma concentration of the drug, which will require dose adjustment of the remaining dose.
Dexalgin increases the level of cardiac glycosides in the blood.
Prescription of the drug should be carried out no earlier than 8-12 days after the administration of Mifepristone or other monoamine oxidase inhibitors.
The combination of the drug with ciprofloxacin may lead to the development of convulsions.
The drug may exhibit nephrotoxicity to cyclosporine and tacrolimus.
Ampoules of the drug cannot be mixed with a syringe with Promethazine, Dopamine, Dopamine, Hydroxyzine, Pentazocine, Pethidine through a closed siege. Allowed combinations are with Heparin, Morphine, Morphine, Lidocaine, Theophylline.
You can save dilutions for infusion in plastic containers with ethyl vinyl acetate, low strength polyethylene, cellulose propionate, polyvinyl chloride.

Dexalgin and alcohol

Follow these instructions, the drug should not be taken with alcohol m, because ethanol has a strong toxic effect on the liver and can cause side effects of Dexalgin. For an hour of therapy, you may be able to take alcoholic beverages or ethyl alcohol-based liquors. The procedure should be carried out with care by persons who suffer from chronic alcoholism.

Side effects and overdose

Instructions to note that symptoms of overdose with dexketoprofen include sleeplessness, boredom, disorientation, anorexia, confusion, headache and abdominal pain. Symptoms can be eliminated by rinsing the mucus, hemodialysis, and symptomatic therapy. Side effects from administration of Dexalgin:

thrombocytopenia, anemia, neutropenia;
paresthesia, restlessness;
superficial thrombophlebitis, arterial hypotension or hypertension, peripheral swelling, heat, tachycardia, skin hyperemia, extrasystole;
dyspnea, bradypnea, bronchospasm;
liver or hypothyroidism, fatigue, nausea, vomiting, abdominal pain, anorexia, dyspepsia, bleeding, ulcers and perforations of the grass tract, diarrhea, baking;
nephritis, polyuria, nephrotic syndrome, nitric acid;
destruction of the prostate; disruption of the menstrual cycle;
fleshy spasms, difficulty moving the joints;
allergies, photosensitivity, dermatitis, acne, irritation, sweating;
kropivyanka, angioneurotic plaque, Lyell or Stevens-Johnson syndrome, anaphylactic shock;
ketonuria, proteinuria;
hypoglycemia, hyperglycemia, hypertriglyceridemia;
individual's mark;
muscle pain, injection, inflammation, hematoma, hemorrhage.

Contraindicated

The drug is used with caution in patients with a history of allergies, disorders of the hematopoietic system, systemic hematopoietic disease, weakness to hypovolemia, ischemic heart disease after 65 years. Instructions for use include the following contraindications:

viraza 12-fingered intestine and schluka;
severe damage to the liver, nirok;
vacancy, lactation, child's age;
severe heart failure;
active bleeding; anticoagulant therapy;
nonspecific virazkovic colitis, Crohn's disease;
bronchial asthma;
hemorrhagic diathesis, impaired blood flow;
hypersensitivity to the components of the drug;
pain syndrome in coronary artery bypass grafting;
epidural, internal or subthecal injection.

Think about selling and saving

The medicine is sold with a prescription. Rozchin is preserved at temperatures up to 25 degrees for five minutes, after dilution - extracted at 2-8 degrees. Pellets and granules need to be trimmed at a temperature of up to 30 degrees, the term of application consists of two factors.

Dexalgin's analogs

To replace the drug, you can choose other non-steroidal anti-inflammatory drugs such as dexketoprofen or other drugs. Analogs to the drug:

Brufen – gel, sachet with powder, syrup and tablets based on ibuprofen;
Bofen - oral suspension in place of ibuprofen;
Dexifen – tablets based on dexibuprofen;
Zotec - tablets that replace dexibuprofen;
Ibuprom - analgesic tablets that replace ibuprofen;
Ibufen – suspension, capsules and tablets based on ibuprofen;
Ibuprofen - tablets, ointment, gel, to take the same substance;
Imet – tablets based on ibuprofen;
Ketonal – formulation, gel, cream, tablets, capsules and suppositories based on ketoprofen;
Nurofen is a gel and tablet that replaces ibuprofen.

Price for Dexalgin

You can add the drug through the Internet or pharmacy kiosks for the price, which is available in the release form for the individual and the number of ampoules, sachets, and tablets per patient. Oriental Moscow prices.

A non-steroidal anti-inflammatory analgesic is Dexalgin. The instructions from the drug instruct you to take 25 mg tablets, injections in ampoules for injections in cases of severe pain. The patient's recommendations and doctors' recommendations indicate that this drug helps in the treatment of pain in arthrosis, arthritis, osteochondrosis.

Release form and warehouse

Dexalgin is produced in the form of a dose for internal lingual and internal injections in dark glass ampoules in plastic pallets of 1, 5, 10 pieces in a cardboard package with instructions. Rozchin is clear with the smell of alcohol.

The main active drug is dexkeprofen trometamol.

Tablets are also produced that are white, smooth, round and convex, with ribs on both sides. One tablet contains 25 mg of dexketoprofen trometamol.

Pharmacological action

Dexalgin has antipyretic, antifungal and analgesic effects. Analgesic action occurs approximately thirty days after parenteral administration. It will take 4 – 8 years before the pain-related effect begins to develop.

After oral administration of Dexalgin, the drug begins to work after 30 minutes. After 0.5 years, the maximum concentration of the drug in the blood is reached. The duration of analgesic treatment begins in an average of 3 – 6 years.

What does Dexalgin 25 help with?

Indications for tablet consolidation include pain syndrome:

rheumatoid arthritis, arthrosis, cyst metastases, osteochondrosis, spondyloarthritis.
after operations;
toothache, menstrual pain;
algodismenorrhea, radiculitis;
Ischialgia and neuralgia.

Injections to the drug are prescribed when it is impossible or unjustified to take the tablets, for example, with post-operative pain, after serious injuries, with narcotic injections.

Instructions for drying

Dexalgin tablets 25 mg are prescribed for individual indications. The average recommended single dose is 12.5 mg (1/2 tablet) given 1 to 6 times per day for 4-6 years, if necessary, or 25 mg (1 tablet) given 1 to 3 times per day for 8 years. The maximum dosage is 75 mg (6 tablets).

In patients with impaired liver function or poor liver function, in those with advanced age, the drug should be started at lower doses - no more than 50 mg per dose. The drug is not intended for trivial stagnation: triviality should not be tolerated for 3-5 days.

Ampules

Dexalgin is intended for internal and lingual administration. Recommended dose for adults: 50 mg skin for 8-12 years. If necessary, the drug can be re-administered at a 6-year interval. The additional dose is 150 mg.

In elderly patients and patients with impaired liver function, treatment with Dexalgin should be started with lower doses; The maximum dose is 50 mg.

The drug is intended for short-term (no more than 2 days) stasis during acute pain syndrome. It is now possible to transfer the patient to internal analgesics.

Rules for the preparation and introduction of divisions

Instead of one ampoule (2 ml), inject the drug thoroughly internally or completely internally by injection for at least 15 seconds.

Dilute 30-100 ml of physiological solution, glucose solution or Ringer solution (lactate). The ingredients should be prepared in aseptic tanks and then protected from the flow of daylight. Dilutions of roses (may be transparent) should be administered by daily intravenous infusion for 10-30 minutes.

Contraindicated

When taking Dexalgin, patients should be advised to:

severe heart failure;
erosive-virazkovic effects on the grass tract;
bronchial asthma;
increased sensitivity to the components of the drug Dexalgin, whereby 25 mg tablets and injections may cause side effects;
hemorrhagic diathesis;
severe damage to the functions of the liver and nirok.

According to the instructions, Dexalgin is contraindicated for children, pregnant women and women who are still growing, as well as for patients who take drugs that interfere with the formation of blood clots and laryngeal blood (anticoagulants ).

Side effects

With strict adherence to the instructions in the instructions and the prescribed dose, side effects in patients do not develop so often. In case of hypersensitivity to the components of the medicinal products, as well as with the drug, the patient may develop the following side effects:

On the side of the heart and blood vessels - decreased indicators of arterial pressure, tachycardia, due to heat and a rush of blood to the appearance, in isolated episodes, disruption of the heart rhythm.
Changes in clinical blood picture – anemia, thrombocytopenia, neutropenia.
Lost throat of blood.
Disruption of the menstrual cycle in women; impaired functioning of the prostate in men.
On the side of the organs of the herbal tract - fatigue, vomiting, loss of vomiting, severe pain in the epigastric region, lack of appetite, dry mouth.
Bronchospasm, poor breathing.
Allergic reactions of the skin - dryness, redness, burning of the injection site, Quincke's stain or the development of anaphylactic shock.
Painful swelling in the area of internal lingual administration of the drug.
Headache, trouble sleeping, confusion, occasional episodes of decreased sensitivity, paresthesia.
Thrombophlebitis or pain during an hour of veins when the drug is administered internally.
Unpretentious camp.
Meat pains.

Children, during pregnancy and breastfeeding

Administration of the drug Dexalgin during pregnancy and lactation is contraindicated. Harrowed from a child's house.

special inserts

Patients with a damaged herbal system or a history of bowel disease require constant monitoring. In case of severe bowel bleeding or viral infection, therapy with Dexalgin should be discontinued.

In case of immediate use of other drugs that are injected into the throat, close medical supervision is necessary. The medication can be administered to increase the level of creatinine and nitrogen in blood plasma. Like other inhibitors of prostaglandin synthesis, Dexalgin can have side effects on the thyroid system, which can lead to the development of glomerulonephritis, interstitial nephritis, papillary necrosis, nephrotic syndrome and acute nephritis ї insufficiency.

During therapy with the drug Dexalgin, a slight increase in liver function tests, as well as a significant increase in the level of AST and ALT in blood serum levels, can be avoided. Therefore, control of liver function is never necessary in elderly patients.

If there is a significant change in the supporting indicators, Dexalgin should be used. Dexketoprofen trometamol can mask the symptoms of infectious diseases.

If symptoms of a bacterial infection or deterioration in self-esteem appear during drug therapy, the patient must inform the doctor.

The skin ampoule contains 200 mg ethanol. Due to possible confusion and drowsiness against the background of treatment, there may be a decrease in concentration and speed of psychomotor reactions.

Medical mutualism

Injections should not be mixed in a syringe with pethidine, promethesine, hydroxyzine, dopamine, pentazocine. Can be mixed with morphine, heparin, theophylline and iceocaine.

Dexalgin 25 (tablets) when combined with salicylates, anticoagulants, ticlopidine, heparin, other NSAIDs, citalopram, low-molecular-weight heparin preparations, pentoxifyline, sertraline and fluoxetine, there is a greater risk of guilt nnya bleeding

Be careful when using sulfonamides, methotrexate, lithia, hydantoins to enhance the toxic effect on the body. Zidovudine, quinolones, cardiac glycosides, thrombolytics, cyclosprorine, related sulfonyl compounds and Tacrolimus should not be taken with the drug without the supervision of a physician.

When mixing the mixture for infusion, avoid the presence of promethazine and pentazocine. Then it’s completely crazy with pethidine, dopamine, hydroxyzine, morphine, heparin, iceocaine and theophylline.

Concomitant use of diuretics and ACE inhibitors may cause acute narcotic deficiency.

Analogues of Likiv

Similar propionic acids include analogues:

Ibuprom Sprint Caps.
Nalgesin.
Ketospray.
Profenid.
Naproxen.
Surgam.
Nurofen Express.
Pedea
Flamax.
Bistrumcaps.
Nurofen forte.
Children's Motrin.
Sanaprox.
Nurofen for children
Flamax forte.
Pronaxen.
Strepsils Intensive.
Bistrumgel.
Flugalin.
Advil.
Fastum gel.
MIG 400.
Febrofeed.
Ketonal.
Ibufen.
Nalfon.
Іbuprom.
Ipren.
Oruvel.
Ibusan.
Nalgesin forte.
Apranax.
Algezir ultra.
Brufen retard.
Ketoprofen.
Deblock.
Ibutop gel.
Rakstan Sanovel.
I tried it.
Fastum
Faspik.
Ibuprom Max.
Burana.
Brufen.
Solpaflex.
Bonifen.
MIG 200.
Dovgit.
Naprіos.
Flexen.
Ketonal Duo.
Artrum.

Wash supplies and price

The average price for Dexalgin (25 mg tablets No. 25) in Moscow is 360 rubles, injections - 285 rubles for 5 ampoules of 2 ml. Available for prescription.

Keep in a protected place out of reach of children at a temperature not exceeding +25°C. Vikorist only insights and barbarous discord. After diluting the ingredients, save a little more than 1 dB at a normal temperature of +2… +8°C. The term of attribution is 5 rocks.

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Dexalgin 25: instructions for use and administration

Latin name: Dexalgin 25

ATX code: M01AE17

Ducha speech: dexketoprofen

Virobnik: Laboratorios MENARINI (Spain), A.MENARINI Manufacturing Logistics and Servicer (Italy)

Updated description and photo: 20.11.2018

Dexalgin 25 is a non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic action.

Release form and warehouse

Medicinal form of Dexalgin 25 - tablets, covered with a film coating: round in shape, biconvex, with separate rhizomes on both sides, with a white color coating (in a blister there are 10 pcs., In a cardboard box there are 1, 3 or 5 tablets hysterics).

Warehouse for one tablet:

active substance: dexketoprofen – 25 mg (in the form of trometamol dexketoprofen – 36.9 mg);
additional components (core): corn starch, microcrystalline cellulose, sodium carboxymethyl starch (type A), glyceryl palmitostearate;
coating: hypromelose, titanium dioxide, macrogol, propylene glycol.

Pharmacological authorities

Pharmacodynamics

The active ingredient in the drug, trometamol dexketoprofen, being a non-steroidal substance, has an anti-inflammatory, antipyretic and analgesic effect. The mechanism of action lies in the non-selective inhibition of cyclooxygenases (COX) - a group of enzymes that participate in the synthesis of prostaglandins, which, in addition to other functions, regulates and mediates the development of inflammatory processes. Dexketoprofen suppresses the effects of COX-I and COX-II.

Relief of painful symptoms occurs within a few days after oral administration of the drug. Therapeutic treatment lasts for 4-6 years.

When combined with opioid analgesics, Dexalgin 25 reduces the need for opioids by up to 30-45%.

Pharmacokinetics

administration: the maximum concentration of trometamol dexketoprofen in plasma (Cmax) after taking the drug internally is reached after 15-60 weeks. With one-hour intake, the absorption of the drug is reduced. The area under the pharmacokinetic curve (AUC) after single and repeated oral administration of the drug is approximately the same value, which indicates the presence of cumulation of the active substance;
distribution: approximately 99% of trometamol dexketoprofen is bound to plasma proteins. The middle section volume (V d) is set to 0.25 l/kg. The period is approximately 0.35 years;
Metabolism and elimination: the metabolism of dexketoprofen is mainly due to its conjugation with glucuronic acid and further elimination by nitric acids in the form of metabolites. The recovery period (T1/2) is approximately 1.65 years. In elderly patients there is a decrease in the clearance of trometamol dexketoprofen and an increase in T1/2 by 48% in the average patient.

Showing before stagnation

pain syndrome of various origins (including post-traumatic pain, post-operative pain, pain with nitric acid, cystic metastases, ischialgia, algodismenorrhea, neuralgia, radiculitis, toothache);
Acute and chronic inflammation, inflammation-degenerative and metabolic diseases of the musculoskeletal system (including spondyloarthritis, rheumatoid arthritis, osteochondrosis, osteoarthritis) - for symptomatic treatment, altered inflammation and pain at the time of stiffening.

Contraindicated

Absolute:

Virazkova ailment of the gut and duodenum at the stage of digestion;
inflammation of the intestines of an inflammatory nature (Virascian colitis, Crohn's disease) at the stage of constipation;
history of bleeding in the scolio-intestinal tract, other active bleeding (including suspicion of internal cranial bleeding); anticoagulant therapy;
impairment of function at moderate or severe stage (creatinine clearance less than 50 ml/min);
manifestations of impaired liver function (according to the classification of Child - P'yu 10-15 points);
severe heart failure;
hemorrhagic disease and other coagulation disorders;
a history (either or not) of bronchial asthma, recurrent polyposis of the nose/sinuses and intolerance to aspirin or other non-steroidal anti-inflammatory drugs (including a history);
the period after the procedure of coronary artery bypass grafting;
gestation and lactation period;
century to 18 rocks;
Individual sensitivity to dexketoprofen, any NSAID or any additional component of the drug has been increased.

In case of illness/situation in which the use of Dexalgin 25 requires caution:

disruption of the laryngeal blood system;
history of allergic reactions;
illness of Libman-Sachs or mixture of sickness of contaminated tissue;
hypovolemia is evident;
history of viral infection of the intestinal tract;
ischemic heart disease;
cerebrovascular disease;
blood diabetes;
hyperlipidemia;
disease of the peripheral arteries;
immediate cessation of other medicinal treatments;
a trivial course of treatment with non-steroidal anti-inflammatory drugs;
alcoholism, evil chicken;
summer century (over 65 years).

Instructions for dosing Dexalgin 25: method of dosing

Dexalgin 25 tablets should be taken internally, within an hour.

Recommended dosing regimen: depending on the intensity of the pain symptom - 1/2 tablet (12.5 mg) every day for 4-6 years or 1 tablet (25 mg) every day for 8 years. Dobov's maximum dose is 75 mg.

Patients with impaired liver function and/or liver disease, as well as elderly patients, are recommended to start taking Dexalgin 25 at lower doses. The additional dose for these categories of patients is 50 mg.

A course of therapy with Dexalgin 25 does not have to exceed 3-5 days. The drug has no indication for treatment.

Side activities

Possible side effects on the side of systems, organs and their frequency is subject to special classification (often - ≥ 1/100 to< 1/10, нечасто – от ≥ 1/1000 до < 1/100, редко – от ≥ 1/10 000 до < 1/1000, очень редко – < 1/10 000, включая отдельные сообщения):

scilicointestinal tract: often – nausea, vomiting, dyspepsia, abdominal pain, diarrhea; uncommon – flatulence, dry mouth, constipation; rarely – anorexia, erosive/virulent disorders of the intestinal tract, virulent bleeding and perforation; very rarely – infection of the subslulline bud;
nervous system: infrequently - confusion, headache, drowsiness, insomnia; rarely – paresthesia;
blood and lymphatic system: very rarely – thrombocytopenia, neutropenia;
organi chuttya: rarely - noise in the ears; very rarely - decreased severity of vision;
Cardiovascular system: infrequently – hyperemia of the skin, due to heat; rarely – displacement of the arterial pressure, extrasystole; very rarely – decreased arterial pressure, tachycardia;
dichal system: rarely – bradypnoe; very rarely – shortness of breath, bronchospasm;
liver and liver: rarely – increased activity of liver transaminases (including aspartate aminotransferase and alanine aminotransferase), liver disease; very rarely - liver damage;
irritations and sechovidnye paths: rarely – polyuria; very rarely – nephrotic syndrome or nephritis;
reproductive system: rarely - disruption of the menstrual cycle (in women), minor disorders of the anterior gland during severe stagnation (in men);
musculoskeletal system: rarely – difficulty in the musculoskeletal system, muscle spasm, back pain;
hide and under skin tissues: infrequently – sagging, dermatitis; rarely - sweating, pimples, kropiv'yanka; very rarely - severe skin reactions (Lyell syndrome, Stevens-Johnson syndrome), allergic dermatitis, photosensitivity, angioedema;
speech metabolism: rarely – hypoglycemia, hyperglycemia, hypertriglyceridemia;
laboratory data: rarely – proteinuria, ketonuria;
the body is swollen: infrequently – nausea, fever; very rarely - swelling, anaphylactic shock;
other: infrequently – aseptic meningitis (important in patients who suffer from systemic worm or mixed tissue disease), hematological disorders (hemolytic and aplastic anemia, purpura); rarely – hypoplasia of the medullary cord and agranulocytosis.

Overdose

If you overdose on Dexalgin 25, you may experience the following symptoms: confusion, headache, boredom, abdominal pain, anorexia, insomnia, disorientation.

Treatment is for symptomatic therapy. If necessary, flush the plug and perform hemodialysis.

special inserts

Patients with a history of illnesses of the scutulo-intestinal tract or with scutulo-intestinal disorders require careful caution during treatment with Dexalgin 25. In case of culprit diseases or scutulo-intestinal bleeding, the drug is used d administrate.

Clinical studies have shown that administration of dexketoprofen simultaneously with low-molecular-weight heparin preparations in the postoperative period in prophylactic doses does not affect the indicators of laryngeal blood loss. When taking a drug with anticoagulants in bed, it is necessary to carefully control the laryngeal blood system.

Dexalgin 25, like other non-steroidal anti-inflammatory drugs, can lead to increased concentrations of nitrogen and creatinine in the blood plasma. As a result of its adverse effect on the reproductive system, through inhibition of prostaglandin synthesis, the drug can cause the development of interstitial nephritis, glomerulonephritis, nephrotic syndrome, papillary necrosis and acute nephritis deficiency.

If, during therapy with Dexalgin 25, one should be careful not to increase the level of hepatic transaminases in blood serum (especially in elderly patients), the drug should be discontinued.

When treated with dexketoprofen, the symptoms of infectious diseases may be masked. Therefore, if you feel depressed or guilty of any signs of infection against the background of treatment with Dexalgin 25, you must urgently go to the doctor.

Floating to the building to the terminal by motor transport and folding mechanisms

After taking Dexalgin 25 (especially in the first year), side reactions such as drowsiness and confusion may occur. Therefore, during treatment with the drug, it is necessary to use transport methods and procedures that require a high concentration of attention and a strong psychomotor reaction.

Stagnation during gestation and lactation

According to the instructions, Dexalgin 25 contraindications for stagnation in pregnant women and women who are breastfeeding, there are some reliable clinical data that confirm the safety of stagnation in There are also categories of patients, daily.

Zastosuvannya at the child’s place

While there is no evidence about the effectiveness and safety of the drug in pediatrics, Dexalgin 25 is not recommended for use in children and under 18 years of age.

If the function of the nirok is impaired

Neurodeficiency of moderate or severe stage (with creatinine clearance less than 50 ml/min) is contraindicated before administration of Dexalgin 25.

In case of impaired liver function

Prescribing the drug to patients with severely impaired liver function (10-15 points according to the Child-Pugh classification) is not recommended.

Zastosuvannya at the Summer Palace

Use Dexalgin 25 tablets carefully in elderly patients (over 65 years of age). For this category of patients, it is necessary to adjust the initial doses of the drug at a lower dose; the maximum dose should not exceed 50 mg.

Medical mutualism

Taking Dexalgin 25 simultaneously with various medicinal treatments can lead to the development of offensive effects:

Other non-steroidal anti-inflammatory drugs, including salicylates in doses greater than 3 g/day: increased risk of viral and intestinal bleeding (through a synergistic effect);
heparin, oral anticoagulants in doses that are more prophylactic, and ticlopidine: increased likelihood of bleeding due to inhibition of platelet aggregation and mucosal damage in the colonic tract ;
Lithium preparations: increasing the concentration of Lithium in the blood to the point of toxicity. When taking dexketoprofen, changing the dose or changing the drug, monitor your thyroid indicators;
Hydantoins and sulfonamides: increased risk of their toxic effects;
Diuretics, angiotensin-converting enzyme inhibitors: increasing the likelihood of the development of acute nicotine deficiency in patients with angiotensin disorders (through a decrease in glomerular filtration rate, which is caused by soulful synthesis of prostaglandins). Dexketoprofen may reduce the antihypertensive effect of certain drugs;
methotrexate: increased hematological toxicity through a decrease in nitric clearance against the background of stagnation of non-steroidal anti-inflammatory drugs. It is necessary to carry out thyroid pumping of blood cells in the first stage of acute bed therapy. In cases where lung function is impaired, as well as when carrying out therapy in elderly patients, careful medical care is required;
sertraline, fluoxetine, citalopram and other serotonin secretion inhibitors, oral glucocorticoids: increased risk of splanchnic-intestinal bleeding;
pentoxifyline: increased likelihood of bleeding. Necessary clinical monitoring and verification of bleeding rates (time of larynx);
Zidovudine: increased risk of its toxic effect on red blood cells, which is thought to be an influx on reticulocytes, with the possible development of severe anemia in the period after taking non-steroidal anti-inflammatory drugs. It is necessary to carry out an initial blood test and a number of reticulocytes after 1-2 consecutive treatments with dexketoprofen;
similar sulfonyl compounds: enhancing the hypoglycemic activity of sulfonyl compounds through their binding to plasma proteins;
low-molecular-weight heparin preparations: increased virility and development of bleeding;
β-blockers: changes in their hypotensive effect through inhibition of prostaglandin synthesis;
cyclosporine and tacrolimus: increased nephrotoxicity, which is due to the action of renal prostaglandins. During the period of sleep therapy, it is necessary to control the functioning of the muscles;
thrombolytics: reducing the risk of bleeding;
probenecid: increased concentration of dexketoprofen in blood plasma due to the influence of probenecid on nitric tubular secretion/conjugation with glucuronic acid. Dose adjustment of non-steroidal anti-inflammatory drugs is necessary;
cardiac glycosides: increase in their concentration in blood plasma;
Mifepristone: a theoretical risk of altering the effectiveness of mifepristone through the infusion of inhibitors of prostaglandin synthesis. Dexketoprofen is not recommended to be taken earlier than 8-12 days after administration of mifepristone;
quinolones: a significant risk of court judgment when taking non-steroidal anti-inflammatory drugs simultaneously with high doses of quinolones (based on the results of experimental studies in animals).

Analogs

Analogues of Dexalgin 25 are Dexalgin and Flamadex.

Terms and minds saving

Store in a protected, light, dry place at a temperature not exceeding 25 °C.

Keep away from children.

The term for saving is 2 rocks.

Instructions for use before injections of Dexalgin 2 ml. No. 5 (with the main active word dexketoprofen trometamol), which is written in the Russian and sovereign language of the skin region, is included in the skin packaging with ampoules, but, unfortunately, is often ignored by many patients before treatment. And for free, even taking and taking drugs from the group of non-steroidal anti-inflammatory drugs (NSAIDs), as if you were experiencing pain, is a great relief. Of course, the drug-free drug dexalgin has good results from patients and positive comments on the forums. From now on, drink with peace of mind and just buy some analogues (maybe even cheaper!) at the pharmacy. However, it is not possible to self-administer internal ulcer or internal injections of Dexalgin, the price of which is quite low - 250 - 400 rubles, and does not lack recommendations from drug dealers.

Important! According to the official instructions before tablets and injections of Dexalgin, they are contraindicated for children, pregnant women and women who are breastfeeding, due to breastfeeding, due to the precautions of summer m people, as well as patients who take drugs that interfere with the formation of blood clots and throat loss (anticoagulants) , with nirkovia nircia. and other illnesses that will be discussed further.

Dexalgin is analgesic, anti-inflammatory and potent and classified as a non-steroidal anti-inflammatory drug, available in 2 ml ampoules or 25 mg tablets.

Important! The drug Dexalgin in ampoules, for internal and internal ulcerative injections and tablets, as well as other drugs of the designated group, should not be taken with serious medical treatment, which is due to the doctor, and The client, in his turn, is obliged to carefully read the instructions from the standpoint and mutuality of the main speech that is given. dexketoprofen trometamol, with other drugs and drugs, especially.

The drug is bottled in amber-colored ampoule bottles of 2 ml. Each 5 ampoules are packaged in plastic containers and a cardboard box.

The drug is stored at temperatures not exceeding 25°C without access to daylight and in a place inaccessible to children and animals for 5 years from the moment of release.

After preparing the drug, it is necessary to use it as carefully as possible. Keep the ingredients at a normal temperature of 2-8 °3 a little more than in a place well protected from light.

Medicine form and chemical. stock

The pharmacotherapeutic group that includes Dexalgin is a non-steroidal anti-inflammatory and anti-rheumatic drug. Dexalgin injections are poured into ampoules of 2 ml doses, which are administered to the patient internally or internally.

The strength of the active substance in the skin ampoule is 25 or 50 mg. To be more precise, one ampoule of Dexalgin 50 contains 73.8 mg of trometamol dexketoprofen, and it contains 50 mg of dexketoprofen (similar to propionic acid).

As we can see with the drug Dexalgin 25 in tablets, it is obviously equivalent to 25 milligrams of the potency of dexketoprofen trometamol.

Increase your respect! In addition to the injective cream, another form of release of Dexalgin is also available in tablets.

In the ampoules of Dexalgin, in addition to the active substance, the instructions from stagnation and storage are mixed with 96% ethanol, followed by chloride and sodium hydroxide (used as a pH regulator), and distilled.

Description of pharmacological power

Instead of ampoules of Dexalgin - this is a clear-cut solution that does not harm the color, it is barn-free.

After Dexalgin is administered internally, after 20 weeks its maximum concentration in the body is reached.

By analogy with other medicinal treatments, which may have a high incidence associated with plasma (99%), the total volume of the active substance in this period is less than 0.25 l/kg. Until the end of life, it will be about 0.35 years. The duration of administration of the drug is 1–2.7 years.

The release is obtained through nitric acids, with the help of conjugation with glucuronic acid.

It's great! After the drug Dexalgin is administered to the patient, dexketoprofen trometamol may appear in the form of the optical isomer S-(+). It should be noted that there is no transformation of the drug in the human body to the optical isomer R-(–).

On the video channel Healthy People - Happy People, they talk about Dexalgin (injections) - Instructions for administration:

Pharmacodynamics

Dexketoprofen trometamol - active substance in ampoules Dexalgin for injections - ce tromethamine salt, which is similar to (S)-(+)-2-(3-benzoylphenyl) propionic acid. The drug has a sedative and anti-inflammatory effect and is comparable to non-steroidal anti-inflammatory drugs.

The effect of this group of drugs is manifested in the suppressed activity of cyclooxygenase, and, as a result, a significant decrease in the synthesis of prostaglandins - substances that provoke inflammation.

It's great! The main version is that, in addition to suppressing the synthesis of prostaglandins, the drug dexalgin also affects other mediators of inflammation, sedation, and kinin. So, for the shell of this stagnation, not only a direct inflow on the burning spot will be ensured, but also in the middleanti-ignitiondiya.

The action of dexketoprofen in laboratory animals and humans as a cyclooxygenase inhibitor has been confirmed experimentally.

What is the impact of the drug Dexalgin on the body as an analgesic?, then it was used both for hypoglycemic, cystic and muscle pain, and during surgical operations (internal surgery, orthopedics, gynecology), as well as with nitric rings. In all cases of mental illness in a patient with moderate pain syndrome, the drug was found to be effective and eliminated positive effects.

The analgesic effect of the drug reaches a maximum in approximately 30-45 weeks after administration and lasts for 8 years, after administration of 2 ml of Dexalgin 50. This is to say about those that with various types of pain, Dexalgin has shown itself during clinical trials try it as a drug that can be used analgesic activity.

KRIM TO, Bulul Klinnically brought, Shcho Dexalgin іn'єktzhyniy in ampoules of the Dziniti dose, the parats, yaki to the Oppiahs of the Osunennya in the PISLAPLAPENECIA PERIODID. When Morphine is administered in combination with Dexalgin, at least 30-45% less of the former is required to achieve the necessary analgesic effect.

Indications for the injectable form of Dexalgin injections

The drug is administered in the form of injections in these cases, unless it is administered orally, for short-term symptomatic therapy of acute pain syndrome of high and medium intensity. Those that Dexalgin helps with, or, more simply, those that are indicated before the drug is used, include the following:

Postoperative pain syndrome;
In other cases, when there is a need for sleep, pain relief for a short period of time - these are the main symptoms, which is why injections of dexalgin internally and internally help.

Method of congestion and dosage

Dexalgin in its injectable form is cured both internally and externally, please write to us about the price in the official instructions for curing the liquids.

Methods of injection:

Medicinal interactions, from which it is necessary to mix

Dexalgin is not allowed to be mixed with pethidine, pentazocine, dopamine, promethazine and hydroxyzine. in small volumes, fragments during such manipulations (for example, mixing in water) are said to lead to the creation of a siege in Russia.

Infusion supplies are not allowed before mixing with pentazocine and promethazine.

Important! Dexalgin injections in ampoules, notallowed before mixing with everyday medicationsat the next division: “Vkazivki shodo zastosuvannya da divordenya”!!!

Vkazivka should use Dexalgin so that it can be diluted and injected

Now let’s take a closer look at why you can give injections of dexalgin internally and internally, read these instructions, why dilution of the drug is allowed:

With intravenous bolus and internal ulcerative methods of administering Dexalgin, take it from ampoules and begin administration immediately.
For injection that works internally, it is necessary to separate without access to natural lightening. in sterile minds.
Dexalgin in small volumes can be mixed with injection agents: theophylline, morphine, heparin(out of the middle of the syringe).
To prepare an infusion dose, 2 ml of Dexalgin is diluted in 30-100 ml of Sodium Chloride, Ringer's lactate or glucose. Breeding is carried out in sterile containers without access to natural daylight. Rozchin may be barbarvless and clear.
Dexalgin, which is already diluted in 100 ml of Sodium Chloride or glucose, can then be mixed with heparin, dopamine, hydroxyzine, theophylline, morphine and pethidine.
Since dilutions of the drug are saved until the moment of administration in: PC, EVA, PENP and PVC bags, changing its concentration for the right minds is not saved.
Dexalgin is indicated for one-time use., then the waste that is lost, as it is wine, is subject to disposal. Before administering the goiter, carefully look at the packaging containing the product, which contains solid particles. The homeland may be open-minded and not a mother of color.

The video shows how to properly administer internal medications, including Dexalgin:

And this video shows how to properly administer the internal ulcerative injection of a drug, a syringe, including Dexalgin:

Method of dosing for adults and summer.

How often can Dexalgin injections be administered internally or internally? It is indicated for patients for short-term stagnation - therefore, it is prescribed for the period of acute pain syndrome and no more than 2 doses, in the form of injections, and no more than 4 doses, in the form of tablets. The patient will then be transferred, if possible, to pain-relieving substitute drugs, which are administered orally, in the form of tablets.

Arr. increase your respect! Injection of dexalgin injections into the bodyno children or childrenwas carried out . behind thisth reasonsyogaEffective action and safety for this category of patients have not been confirmed. Well, the drug is not prescribed.

For adults, the dosage should be 50 mg, so you can administer no more than 1 ampoule of Dexalgin internally or internally, the interval between injections should not be less than 6-12 years, and the additional dose will not exceed and up to 150 mg;

Increase your respect! PobochniEffect of the drugyou candowngradefor rahunokstagnateIminimally possibleeffective dosevprodovzhminimaltime-hour term, necessary for pain relief.

For severe post-operative pain Dexalgin is prescribed to adult patients in combination with opiates at a basic dosage.

Old age patients Most often, you do not need additional treatment before dosing Dexalgin. However, the physiological state of many people of old age sometimes dictates its own rules. In some cases, it is necessary to reduce the prescribed dosage to 50 mg, so that no more than 1 ampoule of Dexalgin can be administered internally or internally (with a mild level of impairment of the function of the drug);
For patients, suffer from pathologies, which is accompanied by a mild level of dysfunction (if in analyzes the level of creatinine clearance ranges between 50–80 ml/min), the total dose is up to 50 mg;

Important! If the patient experiences a decrease in creatinine clearance to a value less50 ml/xv(Middle and important stage), then taking Dexalgin will be contraindicated for you.

For patients who suffer liver failure less than 5-9 b. According to the Child-Pugh scale, then – light and medium level – dosage is limited to 50 mg, so you can administer no more than 1 ampoule of Dexalgin internally or internally. The reception is carried out under the strict control of the liver plant.

Important! If the patient has liver failure at the level of 10-15 points on a given scale, there will be contraindications for taking the drug.

Side effects of pain-relieving Dexalgin injections

All the main side effects have been overhauled, depending on the frequency of the population - from the most common to the extremely rare manifestations of symptoms of side reactions in the body, to pain-relieving injections of dexalgin, and its active speech, what is it, dexketoprofen trometamol:

Pain, burning reactions, hematomas at the site of injection of the drug;
, when taking injections and tablets;
Destroyed dawn (picture smashed);
Black and white and denunciation;
Arterial decline;
Sweatiness, ;
Dermatological reactions - tingling, feeling of itching;
Increased fatigue;
Dyspeptic symptoms - , ;
Swelling of the larynx, when the drug is taken;
Paresthesia;
Hyperhypoglycemia, hypertriglyceridemia;
Stand untiringly, three thousand;
Bradypnea (reduced frequency of breathing);
, and find the boxes;
i perforation of the wall of the scutum;
, fleshy rigidity, a feeling of tightness in the corners;
Impaired prostate function;
Peripheral marks;
, ketonuria;
Relief from the norm during the time of taking liver samples;
and neutropenia;
Bronchial spasm, buttocks;
Hepatocellular pathology.
Toxic epidermal necrolysis (Lyella village), photosensitivity, Stevens-Johnson syndrome, angioedema.

Most often, side effects from stagnation of dexalgin injections arise from the side of the herbal system. Patients with frail age (more often) may experience scholastic bleeding. They also suffer from stomatitis and bumps.

As with all NSAIDs, such reactions occur as: (typical for patients with VLE and other ailments that affect healthy tissue), as well as pathological changes in blood count and hypoplasia I have a cystic cerebellum.

Dexalgin - a drug for doctors and patients

View from Kudryashov N. I. – , 27 years of experience:

"Dexalgin" is a very good non-steroidal anti-inflammatory, pain-relieving drug. In its practice, stasis is mainly used in patients with diseases of the ridge and slopes, when the meat-binding apparatus is inflamed. The most effective injectable form of the drug is in ampoules, for internal and lingual administration. I recommend using caution in case of pathology of the scolio-intestinal tract. The course of treatment with dexalgin should last no more than 5 days.

From London Sergey Viktorovich – chiropractor, 35 years of experience:

Have a nice day. I’ll lose my vodguk. A very good drug for the situation, where the heat is low, and the pain syndrome is very pronounced. It is unbearable for most patients. Check for the pharmacological effect, when administered internally, the result will be 30, which is much higher with intravenous administration. Of course, it is available either orally (in tablets) or in a parenteral form, which bypasses the CT and is injected into the flesh or vein. Unwanted side effects with stagnant dexalgin rarely occur in patients. However, it is necessary to be careful in patients with SCT pathology.

Ostrivska Ganna Anatolievna. Calling the patient - mother.

I'm flying. For my one-year-old mother, the procedure showed multiple hernias in the ridge, including in the transverse lobe. Since my mother is already an active woman in life, sometimes she suffers from such a situation that she develops some kind of “non-distant” disorder, as a result of which she begins to feel pain in the area across and “pulling” her left leg. In this situation, the cream of anti-inflammatory drugs is a necessary analgesic for my mother. Previously, having helped her well with “Fanigan”, she woke up and lost the severe pain in her spine. When I went to the pharmacy, I was prompted by the pharmacist to give me an internal injection with pure “Dexalgin” 2 ml. in an ampoule that I gave to my mother. Already after 30 weeks there was pain in my back. Therefore, I can safely say that Dexalgin is not a strong analgesic. Internal administration has not been tried, but with medications, the effect remains consistent with treatment.

Chernyak Evgen Igorovich. A video about administering the drug to your 88-river grandfather.

I'm flying. I’m amazed that if everyone praises Dexalgin, it might actually help someone. Our situation is slightly different. My grandfather was born in eighty years. Apparently, a bunch of age-old illnesses (varicose veins, liver disease, etc.). And suddenly another sharp pain appeared in the opposite direction. It’s not enough not to scream in the face of the smallest roar. The doctor said that the compression of the spinal nerves is like lying on a bed. Garazd, having examined, made a diagnosis, prescribed procedures, prescribed ointments - it’s a treat. Ale pain will not pass yet. They put a pepper patch on my head, but it didn’t help. We bought tablets "Dexalgin" 25. Fortunately, there are no direct contraindications for anyone with a seizure. They prescribed one or two tablets per dose. The first day it helped, but the next day the severe back pain returned again. After drinking and leaving for two more days, the same effect will occur. Perhaps there is a reason, who knows. Or maybe they gave us counterfeit pills? Although I bought “Dexalgin” from the Central Pharmacy, everything seemed to be original. My special thought is that this is of little help to elderly people.

Olga I.I. Vіdguk about the price and power.

I read on the Internet how much dexalgin for injection costs 5 ampoules of 2 ml - 245 rubles. up to 288 rub. I went to buy it from the local pharmacy. At the pharmacy I paid 497 rubles 8o kopecks. There is nothing better and cheaper than dexalgin.

Clinical and pharmacological group of the drug: NPZZ.

Pharmacotherapeutic group of drugs: NPZP.

During pregnancy and breastfeeding

Dexalgin injections during gestation and lactation are contraindicated for women.

In case of impaired liver function

Dexalgin is contraindicated for severely impaired liver function (10-15 points on the Child-Pugh scale).

In patients with mildly impaired liver function, treatment with the drug should begin with lower doses; The maximum dose is 50 mg.

If the function of the nirok is impaired

The drug Dexalgin is contraindicated before drying, in case of severe impairment of the function of the niro.< 50 мл/мин).

In patients with mildly impaired function, therapy with the drug should be started at lower doses; The maximum dose is 50 mg.

Suspension in children

Contraindications for stagnation in children.

Congestion in elderly patients

With special care, use Dexalgin in elderly patients (over 65 years of age).

Overdose

Symptoms of overdose:, anorexia, abdominal pain, confusion, disorientation, sleeplessness at night.

Likuvannya overdose: symptomatic therapy; if necessary, rinse the pouch, dialysis.

Umovi sberіgannya

Keep the liquids out of the reach of children, out of the reach of children, in a light place at a temperature not exceeding 25°C.

Term of reference to the drug Dexalgin®

The term of reference to the drug is 5 years. Vikorist only insights and barbarous divisions of faces.

After dilution, store for 24 years, at a temperature of 2° to 8°C, in a protected place in light and sun.

Umovi implementation

The drug is available in pharmacies with a doctor's prescription.

Whose video is: Dexalgin (injections): video instructions for taking the drug.

Whose video is it: Dexalgin and Ketoprofen?" https://www.vidal.ru/drugs/dexalgin__13873

4. State register of medicinal facilities https://grls.rosminzdrav.ru/Default.aspx

5. Smolnikov P.V. (Comp.) - Adviser on the most important medical issues 2004 r.

6. For ed. G.L. Vishkovsky - System of witnesses "Register of medicinal services of Russia" (Radar "Doctor") 2013-2015 r.

7. Pharmacy and pharmacology. Pavlova I.I. (superintendent) - Likarsky estates. Newest Adviser 2012

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This article is published solely for educational purposes and does not provide scientific material, universal instructions or professional medical care, and does not replace the appointment of a doctor. For diagnosis and treatment, rely only on qualified doctors.

| Dexalgin

Analogs (Generics, synonyms)

Advil, Algesir Ultra, Apranax, Artrosilene, Artrum, Bonifen, Brufen, Brufen retard, Burana, Bistrumgel, Bistrumcaps, Deblok, Children's Motrin, Dolgit, Ibuprom, Ibuprom Max, Ibuprom Sprint Caps, Ibuprofen, Ibuprofen, Ketonal , Ketonal Duo, Ketoprofen , Ketospray, MIG 200, MIG 400, Nalgesin, Nalgesin forte, Nalfon, Napros, Naprobene, Naproxen, Nurofen, Nurofen for children, Nurofen forte, Nurofen, Sanovel, Sanaprox, Solpaflex, Strepsils Intensive, Sur gam, Faspik, Fastum, Fastum gel , Febrofid, Flamax forte, Flamax, Flexen, Flugalin

Recipe (international)

Rp.: Sol. Dexketoprofeni 0.05 - 2 ml
D.t.d.: No. 5 in amp.
S.: Enter internally.

Rp.: Tab. Dexketoprofeni 0.025
D.t.d.: No. 10
S.: Take 1 tablet daily.

Pharmacological action

Dexalgin is a non-steroidal anti-inflammatory drug, an inhibitor of the cyclooxygenase system.
It exhibits anti-inflammatory, pain-relieving and antipyretic effects. Dexalgin begins to work when taken orally for 30 minutes. The effect lasts for 3-6 years. Cmax when taken orally is reached after 30 quilins (for the average person – 15-60 quilins). The period of development and growth in the tissues of the body is approximately 1.65 and 0.35 years.
Associated with glucuronic acid. Eliminated by nirks. Do not be careful about accumulation in textiles.

Method of curing

For adults: Pigulki
Install individually. The average recommended single dose is 12.5 mg (1/2 tablet) given 1 to 6 times per day for 4-6 years, if necessary, or 25 mg (1 tablet) given 1 to 3 times per day for 8 years.
The maximum dosage is 75 mg (6 tablets). In patients with impaired liver function or poor liver function, in those with advanced age, the drug should be started at lower doses - no more than 50 mg per dose. The drug is not intended for trivial stagnation: triviality should not be tolerated for 3-5 days.
Ampules
Dexalgin is intended for internal and lingual administration. Recommended dose for adults: 50 mg skin for 8-12 years. If necessary, the drug can be re-administered at a 6-year interval.
The additional dose is 150 mg. In elderly patients and patients with impaired liver function, treatment with Dexalgin should be started with lower doses; The maximum dose is 50 mg. Dexalgin is intended for short-term (no more than 2 days) administration during acute pain syndrome. It is now possible to transfer the patient to internal analgesics.

Rules for the preparation and introduction of divisions
Instead of one ampoules (2 ml), administer deeply internally.
Instead of one ampoule (2 ml), administer by continuous internal injection for at least 15 seconds.
Instead of one ampoule (2 ml), dilute with 30-100 ml of physiological solution, glucose or Ringer solution (lactate).
The ingredients should be prepared in aseptic tanks and then protected from the flow of daylight. Dilutions of roses (may be transparent) should be administered by daily intravenous infusion for 10-30 minutes.

Showing

- reduction of pain syndrome of various origins (including postoperative pain, pain with metastases in the cyst, post-traumatic pain, pain with nitric acid, algodysmenorrhea, ischialgia, radiculitis, neuralgia, tooth niy bil);

- symptomatic treatment of acute and chronic inflammatory, inflammatory degenerative and metabolic diseases of the musculoskeletal system (including rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis).

Contraindicated

Individual sensitivity to trometamol dexketoprofen, other components of the drug and other non-steroidal anti-inflammatory drugs;
. erosive-viral disease of the sclero-intestinal tract;
. bronchial asthma;
. severely impaired liver function;
. coagulopathies (hemorrhagic diseases and others);
. severe (moderate) impairment of the function of the nirok;
. taking anticoagulants;
. child's age;
. heart failure is serious.

Side activities

On the side of the herbal system: pain, abdominal pain; Rarely - erosive-virazonic levels of the SCT.

On the side of the central nervous system and peripheral nervous system: headache, confusion, nervousness, sleep disturbance, paresthesia.

On the side of the cardiovascular system: heartbeat, displacement of the arterial pressure.

Allergic reactions: skin drizzling, bronchospasm.
Others: chills, swelling of the ends, photosensitivity; Rarely – change in the peripheral blood picture, disruption of blood function.

Vipusu form

Dexalgin inject is available as a dose for injection or as a concentrate for preparing an infusion solution. Wine is produced in packages of 1, 5, 6, 10, 20, 50 or 100 ampoules of color glass (type 1); One ampoule contains 2 ml of bark-free clear solution. Not all package sizes may be available for sale.

UVAGA!

The information on the page that is viewed is created solely for educational purposes and does not in any way imply self-indulgence. A resource for informing health care practitioners with additional information about these and other medications, which have promoted the level of their professionalism. The use of the drug "" in obligatory order requires consultation with a physician, as well as his recommendations on the method of curing and dosing of your chosen medicines.