What to use with duphaston in case of hyperplasia. What preparations for the treatment of endometrial hyperplasia are vicorous? Hormonal treatment of endometrial hyperplasia

Hyperplasia of the endometrium is the growth and sweating of the walls of the ball of the endometrium, which is kind and viable through the settlements of the lining of the healthy tissue. The reason for such a phenomenon is found in a disturbed hormonal background, connected with the supernatural synthesis of the hormone of the first phase of the menstrual cycle - estrogen. Estradiol itself starts the proliferative phase, as it is characterized by thinning of the walls of the mucous membrane, active development of the follicular apparatus in the ovaries. go into the secretory phase, but a large amount of estradiol predominates the synthesis of progesterone. With an unacceptable hormonal background in estrogen, doctors prescribe progesterone preparations. One of the most effective benefits is that, with regular intake of drugs, the drug will fill up the deficient hormone of another phase, after which it is possible to effectively treat hyperplasia, like vinicla.

Ways of likuvannya ill

Dane ill can be blamed in any age, but most of all, to the new sill of a woman of reproductive age from 18 to 35 years. The main reasons that provoke endometrial hyperplasia:

  • Hormonal imbalance
  • Be-yakі іnshі endocrine disruption
  • Obesity and diabetes
  • Surgical interventions, which were previously performed on the female organs.

The sickness begins to manifest itself from various disorders, related to the menstrual cycle. The back of the head is blamed for light bleeding during the period of menstruation, for a long time. Blood may come out in clots. Over the years, such a part of blood loss causes increased weakness in the body, confusion and severe deficiency anemia, shards of great blood loss cause a microelement in the body. For the presence of such a pathology, it is impossible to take into account the guilt of the plaid.

Therapy of this disease is directed to us in front of:

  • Impairment of the pathological process
  • Jubilation of in-line illness
  • Adoption of pain symptoms and improvement of the menstrual cycle
  • Prevention of evil neoplasms.

Most doctors prescribe hormonal control using methods of conservative medicine. They can be combined with oral contraceptives, synthetic exogenous gestagens, anti-estrogens and gonadotropins. Apply trade names of combined oral contraceptives: regulon, Logest, . Apply the trade names of synthetic exogenous progestogens: you can also administer preparations of natural progesterone - and progesterone in injectable form. Apply trade names of gonadotropic hormones: , goserelin, . Be aware of the anti-estrogenic powers: gestrinone, danazol, tamoxifen.

We are looking forward to seeing duphaston as a modern progestogen drug, which gives good results with the fewest possible side effects. The active active component in the warehouse is dydrogesterone, which does not show any manifestations of metabolic power, does not cause headaches in most cases, severe heaviness in the breasts, does not affect ovulation, does not have a contraceptive effect, and is also least affected by colivan no wag. A valuable effect is those that the medication does not inject into the indications of blood clotting, does not dissolve blood clots, this can be safely recognized by women who are slender to varicose veins.

Hyperplasia of endometrial lumen, first stage

Pochatkov meta in the treatment of this disease - the fight against bleeding. At the cob stage of therapy, combined oral contraceptives are taken on the cob with medications, they are taken three times a day, but less than half a day. If there is no improvement, then women are shown diagnostically vibrating the mucous membrane of the uterus. At your own discretion, diagnostic visceral can be shared at the likuvalne and razdilne. Razdіlne vyskrabluvannya transferring tissue collection from the mucous membrane of the uterus and the cervical canal. A jubilant procedure for transferring good-natured new creations under the hour of manipulation.

For severe or severe bleeding, the patient takes blood spinal drugs - coagulants. They can be seen: a synthetic analogue of vitamin K - vikasol, as well as etamzilat (dicynone). In critical situations, a blood transfusion is prescribed. Dodatkovo obov'yazkovo are prescribed vitamins of group B and ascorbic acid.

Another stage of therapy for illness

For the period of another stage of treatment, medications are prescribed to transfer the endometrium from the proliferative phase to the secretory phase. This group of people is actively changing the sweat and growth of the endometrium. The drug is taken individually, depending on specific features of the disease in the patient. Duphaston chi yoga is the most commonly prescribed natural progesterone analogue - utrozhestan. Best of all, having recommended duphaston to herself. Vin does not give androgenic and estrogenic effects on the woman's body. Yogo can be drunk absolutely for whatever the conditions are, due to the lack of moisture in the body progesterone.

Take advantage of the most effective in case of hormonal deficiency, menstrual cycle disorders and growth of the mucous membrane of the endometrium. This drug is also effective in combating bleeding caused by ailments. Oskіlki likki do not change the present vaginess, it can be victorious both at the stage of planning, and after the beginning of conception (only in the 1st trimester of winemaking). With a correctly selected scheme, I will receive that dosing zasib without any side effects. The only contraindication for yoga is increased sensitivity or individual intolerance to the drug.

To restore a normal state for the presence of endometriosis in women of indications, take duphaston in a quantity of 10 mg 3 times per doba, starting from the 5th day of the monthly cycle, ending on the 25th day. Such jubilation can be done even less than pivroku. In lonely episodes during the hour of therapy, a woman may experience weakness, confusion, headache, migraine, or sleep disturbance. It is not included, that the sensitivity of the breasts is caused and the sight, that they smear, and then pass from time to time. As soon as after a few months I will not become polluted and side effects will also grow, then I will check and be replaced by a different analogue. Utrozhestan, a natural progesterone without a contraceptive effect, and norcolut, a progestogen with a contraceptive effect, can be considered as the closest analogues.

The third stage in the therapy of a woman

The third stage of the treatment of endometriosis is directly related to the resumption of normal ovulation, which means that the menstrual cycle has returned to normal, and the reproductive function has been restored. Without ovulation, current vaginess becomes impossible. Duphaston itself and ensures the normal renewal of the monthly cycle. Vіn zabezpechuє stіyke drop estradiol to normal values, if indications of the hormone progesterone increase. When reaching the optimal hormonal balance between two hormones, an adequate monthly cycle is ensured.

After the announcement of the monthly cycle of the woman in the general language order, I can come to the obstezhennia at the gynecologist with the method of rechecking the state of the woman's organs. The revision is mainly for additional ultrasound examination, which the gynecologist determines if the hormonal imbalance does not start again, and if the mucous membrane does not start to grow. The liquor obov'yazkovo freezes the skin of the endometrium.

Hyperplasia of the uterus can be the cause of bezpіddya and uterine bleeding. Deyakі vidi giperplazії vіdnositsya to precancerous stanіv. That is why the evil process is not included.

Therefore, the exaltation of hyperplasia of obov'yazkovo may be carried out. The choice of therapy schemes is considered to be a form of pathology, and for the first time women, the manifestation of concomitant ailments and general health.

Understanding about pathology

After the procedure

After blood-spinning preparations and antibacterial therapy are prescribed. Then it is necessary to vicorate the hormones, which is necessary for the usunennia imbalance of hormones, which will prevent the re-growth of the inner ball of the uterus.

In the reproductive period, Zhanin, Regulon, Yarina or Trekvilara are prescribed. Woman after 40 indications for duphaston, norculot, Utrozhestan. AGnRG is behind the indications of vicorist.

Without vishkribannya

Today, in the past days, vyshkribannya can be replaced by minimally invasive methods of likuvannya. Useful stinks are prescribed only, as the patient does not have any other contraindications before the procedure.

Cryodestruction

Using this method, we understand the use of rare nitrogen, to produce a sprout until the frozen inner ball is frozen, and then until it is released from the empty uterus.

Laser ablation

Under the influx of the laser pulse, the hypertrophied caravans collapse and step by step the names rise. Injection of the laser to the point where the mucus membrane is further inspired by the natural order.

Hysterectomy

This term refers to the removal of the uterus. Possibly less vidalennya of the uterus, without ovaries. The uterus at once from the appendages can be seen, as a result of adenomatosis or oncology.

Folk medicine

Recipes of folk medicine are guilty of being the main method of healing. Fitobori supplement either surgical or conservative treatment. Only in this way can one achieve great results.

How to take a boar uterus?

Hog's uterus or ortilia is one-sided to avenge the mass of brown micronutrients and vitamins, including phytohormones, for the female organism.

In case of hyperplasia, the alcohol tincture of ortilia or widvar is used:

  • It is necessary to cover the dried leaves with the stems and flowers of the hog uterus and fill the burners with pivlitrom or cognac. Butel is taken in a dark place for 15 days, but at the same time it is necessary to shake it energetically. Through the introduction of the term, the tincture is processed, taken її on a teaspoon three times a day. The tincture is washed down with water. Trivality of the course - three months.
  • A table spoon of dried spruce is poured with a sprinkle of okrop and is also boiled in a proper fire for 15 strands. After reaching the drink, it should be divided into three doses, the skin should be drunk a year before. Such a jubilation is three at least a month, then after a two-hour break, repeat this next.

Narodnі zasobi against zalizistoj form

The saline form of hyperplasia is considered one of the simplest, so it is easier to get into it for the help of folk methods.

Ailments in many patients are found in the presence of a variety of drug treatments and a complex of old prescriptions. All chickens for trivality trivaє 4 months.

  • First month next to drink fresh juices from beetroot and carrots. You should drink 100 ml a day. Before їzhey approximately for 20 hvilin dvіchі on the day next drink on a spoon olіyu іz nasіnnya lyonu. Oliya is washed down with boiled water. For two days, douching is carried out with tincture of purity (up to three liters of warm water and then add 30 g of tincture). At the same time, it is recommended to drink nastiy, preparations with 700 ml of cahors, 400 g of juice from aloe leaves and 400 g of bjolin honey. The qi components after mixing are infused for two tizhn, drink nastiy for two or three tablespoons per day.
  • For another month It is necessary to transfer more than necessary to add to the hog's uterus.
  • Starting from the third months include douching.
  • At the beginning of the fourth every month, all the lust is pinned on the day, then the month I drink the infusion of the upland uterus and oliya.

There were still few other folk recipes for the healing of GE, but it’s better to consult with your doctor before them.

Why do you enjoy homeopathy?

Vykoristannya homeopathic preparations often give bad results pіd hіkuvannya GE. But it is necessary to take care that it is less likely to happen to that person, as a homeopathic doctor is engaged in similar jubilations.

Skin patients need to take a homeopathic approach so that the drug itself in this way will help to get rid of ailments.

The main emphasis in choosing homeopathy as a way to treat hyperplasia is to strive for stabilizing the level of hormones, for normalizing the functioning of the liver and the nervous system.

Most often, doctors prescribe such drugs as Mastomerin, Acidum Nitricum, Kalium carbonicum, Genikocheel. Deyakі from them it is recommended to take after the end of the course of taking hormonal supplements.

How can you see the hyperplasia of the uterus?

The choice of the method of this scheme is rich in why it is a form of endometrial hyperplasia.

Zalizna

Patients with salivary GE undergo a few stages of treatment:

  • Vishkribannya.
  • Hormone therapy with vicarious oral contraceptives and gestagens. Bad results are given by the placement of the Mirena coil. Women older than 35 may have AGnRH.
  • Vitamin therapy.
  • Correction of chronic deficiency anemia.
  • Physiotherapy.

In times of recurrence of the pathology, resection and ablation of the endometrium. Hysterectomy is carried out in case of GE with endometriosis for an hour of menopause.

Zalizisto-cystic

This type of hyperplasia is enjoyed hormonally. Young patients are prescribed progesterone and estrogen for six months.

In the period of menopause, vicarious medroxyprogesterone acetate, it is also necessary to take it up to 6 months. Yakshto likuvannya does not help and the brush continues to grow, it is necessary to recognize the operation.

oseredkova

The vognishcheva form of the disease is treated with medication. If during the control obstezhennі there is no plethora of functional ball, then it is assigned vishkribannya with advancing hormonal therapy.

Polypopular

In case of polypoid form, hysteroscopy is carried out, when special scissors are used to cut through the walls of the uterus polypi. Nadali on trivaliy term prescribe hormonal drugs.

Atipova

It is recommended to use the method of treating atypical GE to lie in the age of a woman, people, and other pathologies. If there is bleeding, then a vishkribannya is carried out on the back. In addition, if Zupinena is bleeding, hormonal therapy is prescribed for a few months.

Operative treatment is assigned, as atypova GE appears in the post-menopausal period. Indications before surgery are also relapses of the disease, the presence of an effect in the replacement therapy.

simple

Simple hyperplasia in a similar form, so the exaltation of these two species is identical.

foldable

To foldable hyperplasia, polypopular, middle, atypical. Vidpovidno and exuberance are picked up by the vikhodyachs from the revealed changes in the mother.

Therapy in premenopause

In premenopause, the function of the ovaries is weakened. Likuvannya GE is guilty in this period of time to begin with a retelny diagnostics, so as to allow the inclusion of other characteristic for this period of pathology.

Call out to declare:

  • Hormonal preparations, yakі koriguyut current menopause and serve as a prophylaxis of plump processes.
  • Vitamins. Particularly necessary Vitamin E, And calcium, stench stimulate the work of the ovaries.
  • Sedative drugs and antidepressants normalize sleep, improve psychological mood.

Vision of the uterus with advancing hormonal release is prescribed for recurrent hyperplasia.

Therapy in menopause

At menopause, choose one of the many methods of healing:

  • Hormone therapy. The dose of hormones is selected individually after histology and in the process of treatment is constantly adjusted.
  • Surgical intervention. In most cases, a visceral bath is prescribed, and a laser can be used to apply other changes to the endometrium. Hysterectomy is performed in case of repeated relapses.
  • Combination therapy option transferring hormones and surgical intervention. Hormone is prescribed to the scapula, which helps to stop the proliferation of endometrium and change the yogo tovshchina. In this rank, a change of operation is required. After removal of the uterus, replacement therapy with hormones is prescribed.

Postmenopausal

In the whole period, the rejoicing begins with vishkribannya. After these manipulations, it is necessary to choose the progestogens, the trivality of them will be accepted to one fate. Krym tsikh preparations of vicorist analogues of GnRH. Under the hour of likuvannya, it is necessary to carry out a control ultrasound.

In case of recurrence of the process, the uterus should be examined together with the appendages. When atypical clitin is detected in the histological analysis in postmenopausal women, an operation to remove the uterus without anterior hormone therapy is indicated.

Dietary eating

In case of hyperplasia of endometrium, it is important to take a special diet with overdose of products rich in antioxidants and omega-3 fatty acids. That is why on the table there are buti riba of fatty varieties and weed from it. Korisna llana oliya, hairy gorіh, nasіnnya lyona.

Estrogen normalizes under the influx of products, rich in cellular tissue. Brown low-fat meat, low-fat sour-milk products. Nebazhano їsti malt, borosno, margarine, red meat, spices, lubricated herbs.

You can’t transfer it and navantage the liver with an important one. Also, drink up to two liters on the doba, while on the table there are fresh fruits of the dew.

Hyperplasia of the endometrium of the uterus (HPE) is one of the pathological gynecological conditions, if there are abnormal processes of growth of the inner ball of the uterus. The main reason for this is hormonal imbalance, which is manifested by an overabundance of estrogen and an insufficient amount of progesterone. In order to galvanize the process of tissue growth and endometrial vicarious growth, building up hormonal respiration. Duphaston in case of hyperplasia of endometrium is used to control progesterone to the required indications.

With a normal physiological mechanism of the menstrual cycle, estrogen in the sinus phase of the cycle is used to such changes in the endometrial tissue, so that the ovary occlusion would be easier to creak. The uterus grows endometrium. Growing up, growing in wine, supplemented with ridges, becoming more fluffy for the rahunka, full of bloodshed. If the fetal egg is not implanted, the proliferative phase is under progesterone, if the clitin ball grows, changes the secretory one, if a significant part of the endometrial tissue begins to collapse and exit the uterus before the hour of the month.

As well as zaplodnenіy ovatsіlіtinі vdaєtsya zakripiti in the uterus, progesterone sprijaє process maturation of endometriyu and cob normal perebіgu vagіtnostі. When the correct balance of hormones in the tissue in the mother is damaged, hyperplastic changes are detected, abnormally growing, but there is no complete collapse.

Therefore, in women with HPE, acyclic bloody visions appear, or they are blamed for uterine bleeding after zatriki. Through significant blood loss, anemia develops in patients, which is accompanied by weakness, confusion.

Yak de Duphaston

Duphaston is a target medicinal product, which is an analogue of the hormone progesterone, which is vibrated in the female organism. Speech is chemically synthesized - dydrogesterone, for its molecular and pharmacological powers, similar to natural progesterone.


When taking Duphaston, the body removes a supplementary portion of progesterone, which allows the body to absorb yoga deficiency in the body and eliminate hormonal decay. For the growth of this pathological growth, the endometrium ball is easier to trade and normalize the cyclicity of the process.

The specificity of the progestogenic activity of Duphaston affects its vibrancy itself on endometrial tissue. Therefore, on the basis of other drugs, Duphaston may have a minimum of negative side effects.

Vіn do not repair estrogenic, androgenic, corticoid disorders. The treatment of endometrial hyperplasia with Duphaston is attributed to the fact that it is selectively injected into the estrogen-deposit of endometrial growth.

Appointment of Duphaston for the presence of thin endometrium.

In women of reproductive age, another pathology may develop, proliferating to the appearance of endometrial hyperplasia, as it is associated with thinning of the tissues, called hypoplasia. The problem of thin endometrium negatively affects the possibility of current vaginess, so that the fruiting egg can easily be fixed in a thinned mucus ball. In order to prevent endometrial growth, doctors recommend taking hormonal drugs to avoid estradiol. For example, the use of Femoston in the first phase of the cycle sprays blood circulation in the uterine tissues, promotes the activity of colitis, and increases the thickness of the endometrium.

Duphaston is prescribed to drink in another phase of the cycle. Why does yoga not need to be praised earlier? To that, the popularity of Duphaston is not in the growth of the endometrium, but in the necessary supplementary doses of progesterone, so as to saturate the morning zygote (zaploid ovum) in the uterine ball, in the thin endometrium. Diya Duphaston like bi "curves" the endometrium for the mating of the fruiting egg.

Even if it didn’t stop, the doses of progesterone, which were added to the body of the call, increase the growth of the endometrial ball, speed up the recovery and menstruation begins.


Growth of the endometrial ball is possible for a non-trivial period, so that the doctor correctly takes effective hormonal preparations and, together with the patient, develops the schedule of his admission.

It is not possible to take Duphaston on your own, it is necessary to trust the choice of medications to trust the drug. When there are pathologies associated with endometrial hyperplasia, Duphaston's dotality is recognized to lie due to various factors, which is the responsibility of the doctor.

Circumstances of the patient, the presence of concomitant gynecological diseases, as well as extragenital pathologies, which can be associated with respiratory diseases in vibrable hormones, for example, thyroid disease or supramental diseases.

Duphaston's advances

Duphaston is an effective modern drug that does not have side effects that dominate a number of early pharmaceutical developments, like avenging progestogens. Imovirnist occurrence of side processes of the drug is significantly reduced. The main drug of speech - dydrogesterone is similar to progesterone, and not to testosterone, which ensures the safety of the androgenic activity of the drug and the effects of non-negligible symptoms in the appearance of hirsutism, moderate hair loss, seborrhea , visipu vugriv (acne). When taking Duphaston in courses for a few months, patients rarely notice:

  • headache;
  • nudoti;
  • engorgement of milk worms;
  • zbіlshennya vaga.

Duphaston is allowed to be taken by patients who have somatic pathology, as well as atherosclerosis, diabetes mellitus, gum disease, varicose veins, problems with nirks.

The drug does not have a contraceptive effect, therefore it does not create a transition for conceiving that current pregnancy. At the time of the need to live, you should come to save your vaginess, you can join them with the exaltation of Duphaston.

The drug is well absorbed from the mucosal-intestinal tract and quickly swallowed into the bloodstream. It is important to see out of the section.

Additional doses of dydrogesterone can successfully treat endogenous progesterone deficiency. In case of dydrogesterone:

  • do not have a negative impact on the coagulation process, so do not change the symptoms of blood clotting;
  • does not disrupt carbohydrate metabolism;
  • more sparingly for the liver;
  • do not disrupt lipid exchange.

Regardless of the good results of clinical trials, the use of the drug does not include the appearance of possible negative reactions, but stinks are rarely observed, for example:

  • manifestations of swelling;
  • shkіrnі vysipannya vglyadі kropiv'yanki;
  • dyspeptic become;
  • discord of monthly cycles;

How to take Dufaston in pathology of hyperplasia

Correction of hormonal indications in pathology of endometrial hyperplasia may be clearly primed and competent, so Duphaston should be taken exclusively for the indications of drugs.


Schemes of treatment are individual, protect the prospect of further functioning of the childbearing function and can be taken one-hour by taking the drug with other faces:

  • Standard scheme To protect the menstrual function of a woman and the ability of a mother to a child, it is necessary for women of reproductive age to take pills, starting from the 16th to the 25th day of the cycle, 1 or 2 pieces per doba (10 or 20 mg). If necessary, the mode of admission can be changed for the period from the 5th to the 25th day.


  • Treatment of endometrial pathology in premenopause administer 2 or 3 tablets per dose (20 or 30 mg) in the period between the 5th and 25th days of the cycle, or from the 16th to the 25th. Vikova perebudova lead the woman's body to the extinction of the childbearing function. The amount of estrogen changes, which disrupts the ovulation process: the egg cannot be released from the follicle. The process of development of the zhovtogo body ceased to be povnotsіnnym, now, progesterone production is broken. At the same time, inducing low estrogen levels can counteract the development of hyperplastic processes in the endometrium, which is confirmed by clinical findings.

As a rule, the trivality of the likuvannya becomes close to the pivroku, and sometimes the more trivaly course is required, up to 9 months.

Based on the results of regular obstezheniya (biopsiya endometriya, transvaginal ultrasound), it is recommended to spend 3 months on the cob skin treatment with Duphaston, the doctor examines the duration of treatment with this drug, change the dosage or change yoga to something else.

It is not easy to make a decision if the treatment of endometrial hyperplasia requires surgical methods, but if there is a repeated recurrence of the disease, or because of the presence of significant atrophic changes in the uterine balls, it is necessary to listen to the doctors.

Pathology of the endometrium, which is necessary for the prevention of negative, and sometimes unsafe, consequences of a woman’s health, is resolutely turned for a thorough treatment of methods.

Likarskiy zasib Duphaston (dіyucha rechovina: dydrogesterone) is an analogue of the natural hormone progesterone.

Zastosovuєtsya for treatment of gynecological diseases associated with progesterone deficiency. Gives a good therapeutic effect when simple typical endometrial hyperplasia in patients of childbearing and older age.

What is endometrial hyperplasia?

Endometriy - the inner lining of the uterus. Until the end of the skin menstrual cycle, the functional ball of the endometrium collapses and is traded in the blood. After menstruation, under the influx of estrogen, wine grows again. Until the middle of the cycle of renewal of the endometrium, under the influence of progesterone, it attaches its own growth and transforms from growing (proliferative) into secretory.


When the hormonal "estrogen / progesterone" is disturbed, the balance of the endometrium grows and develops incorrectly, becomes incompetent.

Hyperplasia of the endometrium- tse sickly estrogen-deposit growth of the inner ball of the uterus. Hyperplasia is associated with pathological reproduction of clitin endometrium, deformation and dysfunction of uterine folds. Through hyperplasia, the structure of that robotic endometrium is destroyed.

Illness manifests itself with dysfunctional uterine bleeding, infertility.

The breadth of endometrial hyperplasia in the middle women of different age groups is 30%. In the period of perimenopause - 50%. Deyaki forms of hyperplasia are shy to evil degeneration. Against the background of hyperplasia, endometrial cancer develops more often.

Officials for the development of tsієї ailments are not leftover. An important role in the pathogenesis is played by estrogen: infection by infusion of estrogen in the uterine mucosa and insufficiency of progesterone.

The axis of why drug treatment of endometrial hyperplasia is directly directed at the elimination of progesterone deficiency and improvement of hormonal balance.


Monthly hormonal balance of estrogen/progesterone

The most common therapy for typical endometrial hyperplasia is to carry out "pure" gestagens. A number of hormonal ashes, qi zasobi regulate the work of the female reproductive system and the whole organism as a whole.

Dydrogesterone (Duphaston) is the drug of choice for monotherapy of simple endometrial hyperplasia without atypia.

Treatment of endometrial hyperplasia with Duphaston

Dydrogesterone is the most important progestogen. However, dotsіlnіst zastosuvannya lie in the morphological form of endometrial hyperplasia.

Efficiency of Duphaston for various forms of endometrial hyperplasia.


Efficiency of Duphaston

Chim garny Duphaston?


Duphaston and Norkolut for treatment of endometrial hyperplasia

In this hour, dydrogesterone is the most safe and well tolerated synthetic gestagen. For its structure, it is close to natural progesterone by its power. Yogo temple progestogenic activity is specific: won vibrating directly on the endometrium. To the very same, the side effects associated with the use of Duphaston are insignificant.

Comparison of popular synthetic progestogens: Duphaston and Norkolut

Power, system effects
Duphaston Norkolut
virobleno progesterone type of testosterone
estrogen effect Hi So
Corticosteroid effect Hi So
Androgenic activity and associated effects: acne, hair loss, seborrhea, hirsutism. Hi So
Anabolic effect: in addition to the number of body fat Ні / Very rare So
Peripheral disturbances Ні / Very rare Often
Influx on lipid exchange Hi Negative
Infusion into the cardiovascular system Minimum Negative
Injection into the blood glottis system Hi Raising the risk of thrombosis
Injected into the rіven tsukra in the blood Hi So
Impact on liver function Minimum Negative
Injection into the nervous system Hi Pomіrno-negative
Ovulation suppression Hi So
Disruption of the menstrual cycle Ні / Correct dosing maybe
Anti-impact effect Hi So
Influx on vagity Sprinkle savings Included

Duphaston, along with other progestogens (Norkolut, Provera, 17a-OPK, in.), at pharmaceutical doses, effectively suppresses estrogen-depleted endometrial growth. Ale, zavdyaki high specificity, well tolerated. At that hour, the effects of the “old” progestogens (headache, tedium, engorgement of milk spots, swelling, swelling at the vase, congested varicose veins, etc.) seem to be streaming.

Acceptance of Duphaston permits patients with various somatic pathologies, including hypertension, diabetes, atherosclerosis, obesity, gallstone disease, nirok pathology, varicose veins, thyroid disease.

How to take Duphaston with endometrial hyperplasia.

  • Inside looks like tablets.
  • 1 tablet of Duphaston is mixed with 10 mg of dydrogesterone.
  • 1 standard package of Duphaston has 1 blister. The blister has 20 needles.

The treatment of endometrial hyperplasia is individual. Yoga prescribes a drug after diagnostic visceral mucosal uterus and histological follow-up of endometrial examination.

Schemes for taking Duphaston with endometrial hyperplasia:

For some scheme of drinking Duphaston with endometrial hyperplasia - prescribe a drug!

Walks Duphaston
  • In reproductive age:

Duphaston 10 mg per doba (1 tablet per day) or 20 mg per doba (1 tablet per day).
Accept:
- From the 16th to the 25th day of the menstrual cycle.
or
- From the 5th to the 25th day of the cycle.

This mode takes care of the menstrual and childbearing function of the woman.

Likuvannya Duphaston can be continued for a full hour of vagity. In the period of breastfeeding, the drug is not recommended.

  • At perimenopause (after 40-45 and up to 53-55 years):

Duphaston 20 mg per doba (1 tablet 2 times a day) or 30 mg per doba (1 tablet 3 times a day).
Accept:
- From the 5th to the 25th day of the cycle;
or
- From the 16th to the 25th day of the cycle.

Standard course of treatment with Duphaston: 6 (more than 9) months.

The effectiveness of the treatment is assessed by the drug after 3, 6, 12 months in the beginning of therapy for additional transvaginal ultrasound and / or endometrial biopsy.

The recurrence of an illness leads to a reconsideration of the tactics of recovery: an increase in the dose of Duphaston, or even replace it with norethisterone (Norkolut, Primolut-Nor), medroxyprogesterone (Provera), in.

Possible side effects of Duphaston:

  • Rarely: allergic reactions (red skin, sverbіzh, kropivyanka, angioedema);
  • Rarely: head bill;
  • Rarely: peripheral swelling;
  • Rarely: dyspepsia, minor damage to the liver;
  • Pochuttya napruzha at the dairy vaults;
  • Dysfunctional uterine bleeding. They stop (rejoice) at an increased dose of the drug.
  • Disruption of the menstrual cycle

Hyperplasia of the endometrium - ill health of the body of the uterus, as a result of which changes in the mucous membrane of the uterus occur. The cause of hyperplastic processes in the endometrium is hormonal disorders that are accompanied by too much estrogen and not enough progesterone. "Dufaston" as a helper in the fight against endometrial hyperplasia is the topic of our discussion today.

The endometrium is a mucus uterus, which is supported by a constant change in the prolongation of the cycle under the influx of hormones in the ovaries. In the first phase of the menstrual cycle, under the influence of estrogen hormones, there is an increase, development of malformations, vessels and endometrial stroma. Estrogens also stimulate the appearance of receptors to progesterone, which occurs in another phase of the menstrual cycle in the body.

Progesterone begins to be synthesized only after ovulation. This hormone is responsible for normal implantation of the embryo in the uterine mucosa. Another is important for progesterone, with adequate infusion on the uterine mucosa, menstruation begins 12-16 days after ovulation. In this way, a whole cascade of important reactions is launched in the woman's body, which ensures the exact and correct passage of the menstrual period: without anterior (before menstruation) and onset (after menstruation) bloody visions that smear. The average (pomorna) number of menstrual visions, the average trivality (as a rule, not more than five days), the presence of pain sensations are indications of an adequate injection of hormones on the uterine mucosa.

Hyperplasia of the endometrium - cestan, when the normal mucous membrane of the uterus is damaged, de, as a rule, the receptors are sensitive to progesterone, and then it is not possible to have a normal injection of the hormone on the mucous membrane of the uterus. As a result, a normal, significant menstrual reaction simply does not occur.

The drug "Dufaston" is an analogue of wet progesterone in the female body. The method of recognition of duphaston is a test without insertion (without operative insertion - removal of the mucous membrane) to “remove” the pathological ball of the mucous membrane of the body of the uterus, while creating an imitation of the normal functioning of the ovaries and viconate the function of the body of the body. Menstruation will be painless, trival, clear doti, docks will not be corrected for the function of the ovaries, docks will not be restored to a normal mucus uterus.

To determine the tactics of treatment of hyperplasia of the endometrium, it is necessary to treat such factors, as a patient, cause damage to the mucous membrane of the uterus (hyperplasia), the nature of the pathology, the clinical picture of the disease, contraindication before that kind of lure, concomitant extragenital pathology and gynecological illness.

Duphaston is an analogue of progesterone in the female body. Metaapplication of the progesterone-containing drug duphaston in case of endometrial hyperplasia - try without viscera to suck the pathological ball of the mucous membrane of the uterus, while simulating the full work of the ovaries, as well as the stomach. It is necessary to take care that duphaston normalizes hormonal decay, and even more than one yoga stasis is not enough, so that the pathological process in the empty uterus will recur.

Standard schemes for stosuvannya dyufaston ¾ a course of taking trials from 3 to 6 months, from 5 to 25 days of the menstrual cycle. It is important to remember that the validity of the treatment, the dosage and the dosage of the dosage of the other drug, the drug is installed, which may be the same picture of the overcoming of the disease and information about the possible contraindication before the drug is prescribed.