Now to stop the medicinal preparation mildronate. Mildronate - indication before zastosuvannya How long can you take mildronat for prevention

Zavdyaks to their own mechanism zastosovyatsya at the exalted contagion of the heart of that vessel, for the promotion of vitality of the body. In the case of patients who have taken the drug, there are those who improve their physical, mental state at the time of transition and the period of rehabilitation.

A medicinal preparation, building to improve and improve the exchange processes that occur in the tissues of the body. This metabolic benefit of the new generation is victorious mainly as a symptom of ischemia.

It was noted that the drug was used to relieve the development of angina pectoris. Speech is active to the drug, meldonium, and pours into the central nervous system, improving cognitive function and rozum activity.

With some disorders, prescribe the drug:

1.Cardiology:

• ischemic heart disease;
• stable angina pectoris;
• heart failure;
• climacteric cardiomyopathy;
• prevention of myocardial infarction

2.Neurology:

• cerebral and cardiac ischemia;
• cerebrovascular accident.

3. Ophthalmology:

• pathological changes in the fundus;
• retinopathy;
• circulatory disorders in dilyantsі sіtkіvki.

4. Pulmonology:

• obstructive changes in legeni.

5. Narcology:

• relief of symptoms of chronic alcoholism

6. Hot practice:

• nerve rupture;
• low cost;
• asthenia, not related to adventures;
• the ambition of athletes.

The drug vikoristovuєtsya not as the main face in case of illness, but as an addition to the treatment.

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Mildronate (experienced by patients who have taken the drug, suggest for improvement of self-esteem) is based on meldonium speech, which is an analogue of y-butyrobetaine, a precursor of levocarnitine, which is found in the warehouse of the skin cells of the human body .

One capsule of the drug to take:

• Meldonium digidratum as a dyuch active speech, 250 mg;
• hanging starch, waving from potatoes, yak rozpushuvach;
• silicon oxide (absorbent);
• strength of calcium and stearic acid, as an additional component.

Capsule warehouse:

• titanium dioxide, yak on top;
• gelatin yak dzherelo collagen.

Which form is issued

The drug is dispensed in two dosage forms - gelatinous shells and ampoules. The capsule of white color has a crystalline hygroscopic powder with a slight odor. Packed capsules of 10 pcs. in contour compact packaging, blister packs. The cardboard bundle has 4 middles, є the instruction from the zastosuvannya is included. Vartist - 300 rub.

A rare form is dispensed in ampoules, for the skin with 5 ml of the drug, indicated for internal injections. In one ml of the preparation, mix 100 mg of fluffy speech, meldonium. Packing variant of 10 ampoules - 300 rub.

Pharmacodynamics

The main effect of the drug is the restoration of the cavities of the damaged blood circulation on the sings of the tissue, the accumulation of the non-nutrient amino acid - carnitine - is deduced. Mildronate, preserving the stability of metabolic processes, reducing the level of carnitine, inhibiting biosynthesis and absorption in nirkah.

Levocarnitine takes part in the oxidation of fatty acids, changing their density, as the main energy source of the myocardium. Carnitine is also involved in the transport of acids across the mitochondrial membrane.

As a result of the change in the oxidation of fatty acids in mitochondria, the cells move to the glycolytic core, which irritates the hearts of the m'yaz vikoristovuvat kisen in the strengthened regime. In addition, meldonium strengthens the building of erythrocytes and sees the sourness.

Meldonium reduces the concentration of glucose in the blood, may have a cardioprotective effect, and attenuate the development of atherosclerosis. The drug constantly trains the heart, preparing the cellular metabolism and membrane structures for survival in the minds of ischemic stress, as it becomes.

The drug may sudinorosis increase due to nitric oxide in the endothelium (inner clitin surface) of the vessels.

Active speech, meldonium dihydrate, pours into the body:

In heart failure Meldonium digidratum increases myocardial sluggishness, including a decrease in the frequency of angina attacks.

Pharmacokinetics

After taking Meldonium digidratum, it is thoroughly wetted, and its bioavailability becomes 78%. Bioavailability in the systemic circulation, and the maximum concentration is reached in 1-2 years after taking it internally.

Synthesis and splitting of speech occurs in the liver, two metabolites are formed in its own. To be administered through nirks, an hour of drinking should be deposited in doses, but no more than 6 years. In the organism of three times, trace concentrations are saved.

Zastosuvannya

Mildronate (reviews of patients who have taken the drug of a better positive), improves the exchange of speech in the heart cells of the heart, improves the energy supply of all organs. As if it were a medical zasib, meldonium is guilty of accepting the recommendation of a doctor, with the improvement of symptoms, symptoms, peculiarities of the patient's body.

For children up to 18 years of age

Oskіlki in medicine were not carried out after the drug was taken in a child, then the sign of it was taken up to 18 years.

For grown-ups

Mildronate for adult recommendations in advanced doses - 500 mg or 2 capsules. It is taken in one dose, vranci, or it is divided into two doses of 250 mg, vranci that day. Oskilki drug may have a tonic effect, it is not recommended to take it in the evenings. The course of likuvannya is more than 14 days. If necessary, you can continue with the reception after 2-3 days break.

In times of impaired blood circulation in the brain, the dose may be reduced to 1 g, which is taken in one or two doses. Likuvannya held in 4 to 6 tyzhniv. People who are engaged in energy-vitrate rozum activity are prescribed 4 tab. for doba (500 mg) for 2 stretches.

In complex therapy for the relief of withdrawal symptoms, a 10-day treatment is carried out, 4 capsules per day.

Mildronate in ampoules vicorates internally, internally and for intramural injections. Faces of additional breeding by fizrozchiny are not necessary. Most often, intravenous infusions are carried out, and internal infusions are carried out during the hour of the day of hospitalization.

For women

Clinical trials of the drug for injection of the female body during the period of pregnancy and the birth of a child in the breast were not carried out, so it is impossible to test it in the qi period.

For summer

Persons with a frail age must take the drug carefully. Many people who are aged 60+ may have chronic illnesses, nirks and liver diseases, after taking the drug, they should be treated with a doctor.

Contraindication

Mildronate is contraindicated in people who may be hypersensitive to one of the components of the drug. The observations of the patients show that in some people, they took a medicinal charge, they received a redemption, they passed quickly.

The drug is contraindicated in people who can increase hypertension through:

• damaged venous flow;
• intracranial hematoma.

For people who may decrease the functions of nirok, liver, follow the guardianship of the faces, first follow the doctor. Chi pouring meldonium into the building keruvati transport zabob, chi zbіlshuєtsya svidkіst psihomotornyh reaktsіy -tsі aspects not vyvchenі and danih nemaє. With alcohol, it is not recommended to take the drug.

Overdose

There is no mention of overdosage reactions, the drug has low toxicity, and no serious reactions are observed.

After injection, in case of increased exposure, symptoms may appear:

• decrease in AT;
• headaches;
• movement of the heart rhythm is fast;
• Severe weakness.

In times, symptomatic treatment is carried out. Doctors are happy to control the work of the liver, and hemodialysis is performed ineffectively, because there may be a high level of connection with blood proteins.

Side effects

Mildronate (feedback from patients who have taken the drug, report about side effects), as a rule, is well tolerated. However, in sensitive people, she is quiet, who, having overdosed, can be blamed for secondary reactions.

Body systems	See reactions	Reaction frequency
The lymphatic system is blood-forming	Eosinophilia (increase in the number of eosinophils in the blood)	rarely
Immune system	Allergy (black skin, sverbіzh, swelling)		often
Heart system	Tachycardia, arrhythmia, hypertensive crisis	rarely
Sudinna system	Decreased AT	rarely
Nervous system	head bіl		often
	overexcitement	rarely
Burning damage	Weakness is hot	rarely
Supporting apparatus	M'yazova weakness, spasms	rarely
Sechovidilna system	Participation in the cutting	rarely

When taking the drug, keep in mind that wines can be influenced by the results of some laboratory and instrumental findings:

• increase the concentration of reactive protein in the blood;
• increase in blood eosinophilia;
• increase triglyceride and cholesterol levels;
• accelerate sinus rhythm at the time of the ECG.

In times of doping control, the drug gives a positive result, which should heal people, like taking the fate of magicians.

Medical interaction

Mildronate (discussion of patients who took the drug can be found on the sides of medical sites) is used with drugs:

• prolonged action (which may have a therapeutic effect);
• antianginal diseases (which increase blood flow to the heart);
• sechoginnimi;
• glycosides (rosly preparations that are used to cure heart failure).

The drug can be combined with drugs that are injected into the blood microcirculation:

• reduce the activity of blood clotting;
• scho vplyvayut disruption of the heart rhythm;
• that pereskodzhayut thrombosis.

Meldonium potentiates antihypertensive drugs and vasodilators:

• nitroglycerin;
• beta-blockers;
• nifedipine;
• nitrates;
• calcium channel antagonists

Nebazhano zastosovuvat one hour meldonium іz tsimi likarskimi zabomami, shards can develop tachycardia and hypotension. And also the building strength of dipreparations, which expands the lumen of the peripheral and coronary vessels, which reduces the arterial pressure.

Wash that term saving

It is necessary to take the preparation away from dry, protected from children. The temperature may overhang +25°C. The term of appurtenance is three times more than 4 years.

Wash your permits from pharmacies

The drug is non-prescription, available for free sale.

Analogues

For the treatment of ailments, with which Mildronat winches, you can zastosovuvat such medicinal remedies:

name	Diya	Who is recommended	Yak accept
Product	Improving the metabolic changes of the myocardium in the minds of ischemia,	It is used as a prophylactic method of attacking angina pectoris in times of trival therapy for ischemic heart disease.	Recommended dose: 1 tab. 2 times for mining at the same time for food
Acgovegin	Activates cellular metabolism, increasing the transport of glucose and acid.	It is used in cases of deficient, cerebral blood circulation disorders, trophic disorders.	1-2 dragee trichi for doba before meals
Riboxin	Take part in the metabolism of glucose, stimulating the exchange processes that develop for lack of ATP.	It is prescribed in complex therapy for angina pectoris, inflamed, primary myocardial damage, alcoholic liver damage.	The drug is taken after 200 mg trichi per day for 2 months.
Mexidol	Contributing to cerebral hemorrhage in case of vegetative vascular dystonia	Appointments for patients with cerebral circulatory disorders, vegetative dystonia, anxiety disorders, caused by neuroses.	The main dose is 250 mg of two per day, not more than 2 doses
Piracetam	Improving memory, respect, practicality, restoring the functions of the brain after intoxication	Zastosovuєtsya on likuvannya rozladіv rivnovagi, lowering memory.	It is taken at the heart, you can divide the additional dose into two doses, the remaining dose is taken no later than 17 years
Sodium adenosine triphosphate	The drug improves the metabolism and energy supply of tissues in the body.	Stop with the method of attacking paroxysmal supraventricular tachycardia.	Administer internally under ECG and AT control
Preparations with active speech, scho diє, meldonium.
Melfor		With symptoms of chronic heart failure, impaired blood circulation in the brain, with symptoms of alcohol syndrome.	For the first 10 days, a prescription for injections is prescribed, and then 2 capsules (500 mg) per dose are prescribed once. Course - 5-6 days
Vazomag	Repair injection on the exchange of speech, changing the symptoms of psychophysical overstress	Vykoristovuєtsya as a monopreparation in complex therapy in cases of cerebral circulatory disorders, with chronic heart failure, reduced rozumova praceszdatnost.	In the first 10 days, it is administered internally, and then 2 capsules are prescribed per dose
Medatern	Antioxidant, metabolic zasib	It is used in neurology, in case of hemorrhagic stroke, chronic insufficiency of blood circulation in the brain, reduced efficiency.	It is prescribed 1 capsule of trichi per day for 4-5 days. Then the dose is increased, the course of treatment is up to 6 days.
Cardionate	Metabolic zasib	In case of ischemic ailment in the warehouse of complex therapy with impaired cerebral blood circulation, impaired blood circulation in the eyes.	With complex therapy, 500-1000 mg 1 or 2 times per doba is required; lituration is carried out up to 40 days.

The tables show specific doses of drugs. The stench changes stalely in the presence of ailments, I will become a patient. Medical research and analogues are selected for the recognition of a doctor, shards of the ability to show a variety of side effects.

Mildronat may have a great number of good reviews. Patients who have taken the drug correctly show a positive effect in the prevention of ischemic illnesses.

Video about the drug Mildronate

Mechanism of drug Mildronate:

Mildronate is a drug that improves the eating of heart meat. To be diagnosed with IXC - ischemic heart disease, Hypertensive disease, vegetative-endocrine cardiomyopathy (especially in women with heart pathology with concomitant endocrine diseases - autoimmune thyroiditis with knotting, post-castration syndrome after the removal of uterine myoma from physical anxiety, with alcohol problems and in ophthalmology - with eye damage in case of uterine diabetes, hemorrhage in the eye of an apple).

Mildronate 10% is prescribed at 10.0 intravenously strumine N 10, then 1 capsule x 3-4 times a day for 1.5 months, in summer 1 caps 2 times a day up to 1.5 months.

Mildronate instructions from zastosuvannya, warehouse, indications, analogues and advice

The drug Mildronate is a medicinal product that is designed to improve metabolism and provide energy to all tissues and cells in the human body. Mildronate vikoristovuetsya with the method of use of insufficient amount of energy and accelerated exchange of speech in tissues with chronic ailments, functional impairments (heart failure, asthma, bronchitis, impaired blood flow to the brain and ocular tissues i).

Warehouse and release form

Release of the drug brand Mildronate is available in three forms:

• The capsules are intended for internal use.
• Syrup of appointments for internal zastosuvannya.
• Іnєktsiyny rozchin.

In the relisting of medicinal forms of Mildronate, the number of active speech under the name of meldonium is equal. Its other name is mildronat. Tse obov'yazkovo is necessary to vrakhovuvat, oskolki іnstruktsija іz zastosuvannya Mildronatu tsyu speechovina і so, like in the first type, and so, like in another.

Additional words to enter the warehouse of the capsules of the drug, remember:

The variety of injections has no additional components. Yogo warehouse includes only two elements: meldonium and purified water.

The warehouse for Mildronate syrup has the following additional components:

The release of Mildronate capsules is carried out in two doses - 250 mg and 500 mg each. In syrup, take 250 mg of active skin 5 ml. In the injection market, 100 mg of meldonium per 1 ml is administered. Capsules of cih likiv are often called tablets. We appreciate that the rest of the medicinal form of this medicine is not available, that capsules = tablets.

Mildronate - instruction on how to apply in various dosage forms

Mildronat: zastosuvannya look like tablets and syrup

Tablets and syrup Mildronate need to be taken internally before meals, or after five years after completion. Apparently, if the drug can cause psychomotor agitation, then it is necessary to take the drug only during the first half of the day. If you need to live Mildronate for a day, then it is necessary to spread it so that the rest of them will not be alive for five years in the evening.

Dosing with congestion of Mildronate

Instructions for stopping Mildronate not to take the drug after the fifth evening. We appreciate that due to the psychomotor awakening, the patient cannot fall asleep. If a person goes to sleep after the twelfth year of the night, then taking the drug can be taken. Protect that before the final dose of the remaining dose of the medicine before bedtime, you will be guilty of less than five years.

Pigulki Mildronate need to be washed down with water, forged with whole milk. Tear the capsules off. Before skin tests, the syrup needs a sprat of times to be afraid, open the lid of the vial and add a sprat of zasobiv. To pour a sprat of syrup, it’s enough to squirt with a peaceful spoon, or we’ll just use a syringe without a needle. At the spoon, pour the required dose of the drug, then drink it.

The average dose of tablets and syrup Mildronate is the same - 250 mg, ingested 2-4 times a day. Ale concrete dosing, the number of priyomіv and the valority of therapy to lie in the presence of ailments, or I will become, through which and vikoristovuєtsya drug. Qi parameters are the same for capsules, for syrup. The choice of the medicinal form of Mildronat develops independently, stalely in favor of the patient, the peculiarities of the organism.

Mildronate: congestion at the sight of injections

Rozchin Mildronate can be administered:

If you administer an injection of Mildronate intravenously, then it will immediately come to the blood. Internal injection means that the introduction of the difference is carried out in the torso of m'yazovykh fabrics, the stars are step by step introduced into the bloodstream. Parabulbar injection means that it is injected near the tissue of the eye. Also, the first two ways to stop the treatment of systemic diseases, and the rest only for the treatment of ophthalmic pathologies.

Іn'єktsiyny rozchin Mildronate is released in one concentration - 100 ml / ml. Also, for the dermal method of administration, the same rozchin is used.

Peculiarities of ingestion of Mildronate in the presence of injections

Ampoules of Mildronate with intermittent opening before injection. Instructions for stowing Mildronate, keeping it safe from the open air on the open air or in the refrigerator. As an ampule of Mildronate was opened earlier than an hour and stood for more than twenty minutes, it is impossible to vicorate.

Implantation of liquids of Mildronate is carried out according to the diagram below:

• With stable angina pectoris - 250 mg three times a day, stretching for a few days. Potim Mildronat is taken in such a dedoze, ale two for the day. In this regimen, the drug is taken for a month. In order to strengthen the effect and reach the maximum effect, it is necessary for the drug to be administered in the presence of nitrates of the trivalent infusion (before them lie Mono Mac, Deponit and others).
• In case of an unstable form of angina pectoris, the drug is administered intravenously in the first doba, after which the patient begins to stagnate Mildronate in the form of tablets or syrup. For the first time, tri-chotiri dobi is administered at 250 mg of birch per day, then Mildronate is prescribed in the same dosage three times a day, twice for this day. The zastosuvannya to a medicine is continued close to six tizhniv.
• In case of insufficiency of coronary blood flow in the acute form in the infarction state - 250 mg of bile per day for six days. In such a period, Mildronat is an additional speech, as it gets used to the warehouse of a complex therapeutic course.
• With pain symptoms in the heart with dyshormonal myocardial dystrophy, Mildronate is given in doses of 250 mg per day for twelve deb.
• When the blood flow is impaired, the drug is administered intravenously for the first ten days, then the patient should be transferred by taking the medication in the form of tablets. You can take yoga 500 mg once a day for six days.

Indications, contraindications, side effects of Mildronate

Indications for injection of Mildronate

Official instructions for zastosuvannya Mildronat recommend the drug, as if a person has such ailments that become:

• Ischemic ailment (Mildronate zastosovuєtsya complex, in combination with other drugs);
• Angina pectoris (drug zastosovuєtsya in a complex way, in combination with other drugs);
• Myocardial infarction (zastosovuetsya in a complex way, in combination with other drugs);
• Heart failure chronic form;
• Pain in the heart with myocardial dystrophy;
• Functional impairment in the activity of the cardiovascular system in patients with a sublingual age;
• Myocardial dystrophy;
• Impaired blood circulation in the brain, which manifests itself in acute and chronic forms (stroke);
• Hemorrhages in the eye of the sitkivka (less than an injection is prescribed;
• Chronic bronchitis;
• low cost of physical practice;
• Asthma;
• chronic alcoholism;
• Hemophthalmos;
• Postoperative period after skin surgery.

In sports activity, the drug Mildronate is recommended to win in such situations:

• Shvidko v_dnovitsya after important advances;
• Overtraining;
• Little practice.

Mildronate: symptoms of overdose

Symptoms of an overdose with Mildronate

For the entire period of treatment with Mildronate, there were no cases of overdosing when ingesting capsules or syrup. With an injectable vicarious drug, an overdose is manifested by the following symptoms:

• Falling arterial pressure;
• Headaches;
• Zamorochennya;
• Weakness.

Likuvannya includes the adoption of symptoms.

Mildronat is well tolerated, because of the side effects due to stosuvannya є rіdkіstyu. Before them, protect yourself like this:

• Allergic reactions (appearance of visipu and vermin, in certain situations Quincke's rash);
• Tachycardia (accelerated heartbeat);
• Falling arterial pressure;
• Weakness;
• Mental arousal;
• Dyspeptic symptoms: trembling, flatulence and other.

Contraindications for vikoristannya Mildronate

• Movement of intracerebral vice;
• The period of vaginess, vigodovuvannya;
• Individual intolerance to the elements of faces;
• Vik less than twelve roki.

How long can you stop Mildronate

The validity of the therapeutic course of Mildronat is to lie down in case of illness, in case of any wines, the patient becomes stagnant. The average course does not exceed two months. If the drug is taken for prophylaxis, then the drug is taken close to the second month. After a singing period, an hour of consultation with a doctor, there may be appointments for a second course of treatment.

Consumption of Mildronate with vagity

Mildronat instructions for congestion of the harrowing are indicated for vagity. It was wisely appreciated that the security of the faces did not go far enough to bring it. Components, which enter the warehouse, penetrate through the placental barrier, so when implanting the preparation of breastfeeding, the baby must be given.

Mildronat: zastosuvannya for children

The drug is conserved to live in persons less than twelve years old. Clinical studies have confirmed that non-compliance with this condition can lead to failure of the heart-vascular system. Also, Mildronate instructions from zastosuvannya do not allow to recognize patients as age up to 18 years old. However, this is only a zahіd of the virobnik.

Likuvalna for the drug Mildronate

The intake of Mildronate does not only speed up the metabolism and the body's tissues with energy, but it also has a therapeutic effect:

• Cardioprotective effect: it protects the cells of the heart from the negative infusion, improves the work and life.
• Antiaginal effect - reducing the need for the removal of sour myocardial cells. As a result, the severity of pain sensations changes, the frequency of attacks decreases with a diagnosis of angina pectoris, and the tolerance of attacks of both physical and emotional nature increases.
• Antihypoxic effect - reducing the negative impact on the deficiency of acid molecules.
• Angioprotective effect - protects the safety of the vessel walls.
• Tonic effect.

Zgidno z іnstruktsiєyu Mildronat, krіm uhogo pererakhovany, vplyvaє і on blood-bearing judges, expanding them and normalizing clitin and immune lanka. Tse allows you to increase the resistance of the body to viruses and infections. In the heart, Mildronate redistributes blood circulation, directing the main volume of blood to areas that control acid deficiency (which regulates ischemia in the mind). Tse posterіgaєtsya not only in the heart meat, but also in the brain, but also in the eyes. Henceforth, it is possible to reach the most optimal blood supply, with the tissue and organs having the necessary amount of sourness, microelements and living components.

As a way to protect the advancement of innovation, Mildronate allows you to ensure the equal balance between the clitin's needs in the otrimann's acidity and yoga in the mist. From the same time, the brains of functioning are created, for some molecules I sour quite enough. Іnshoy power in Mildronate є accelerated elimination of toxins from clitin and tissue protection from prudzhen.

When administering Mildronate for a couple of years after myocardial infarction, Mildronate improves the formation of tissue necrosis zone. Tse shortening period of rehabilitation. In case of ischemic illness and heart failure, the drug increases the strength of the myocardial vein, which is indicated by a change in the number of attacks in angina pectoris.

In case of impaired blood flow in the brain (hostrih, chronic), the bleeding of the vein is reddened, as it appeared to be ischemic (there is a lack of sourness). What effect can be reached with a path to redistribute the blood to the measles of the brain areas.

In case of alcohol withdrawal in patients who suffer from alcoholism, Mildronate can allow the use of functional defects in the functioning of the nervous system:

• Significant tremor;
• Remind me of that respect;
• Normalize the speed of reactions and in.

If Mildronat vikoristovuєtsya healthy people, then posterigaєtsya polіpshenny zdatnostі vtrimuvat znachnі іzichnі vantazhennya і in a small hour vіdnovlyuvatі energy reserves. Mildronate, like yoga, takes a healthy person, promotes practicality, allows you to relieve the symptoms of physical and emotional overstress.

Sumіsnіst Mildronat with other medicines

Zastosuvannya Mildronat potentiates the effectiveness of cardiac glycosides (Strophanthin, Korligon), beta-blockers and others, which are directly related to the change. Mildronate is recommended to take such drugs and reduce the effects of:

• Antianginal drugs (Sustak, Riboxin);
• Anticoagulants (Trombostop and in.);
• Antiplatelet agents (for example, Prostacyclin);
• Antiarrhythmic drugs (Cordarone, Ritalmex);
• Sechoginnі zasobi (Furasemide);
• Bronchodilators (Ventolin).

Preservation is necessary to be observed during one-hour treatment with Mildronate with alpha-adrenoblockers, as a result there is a high level of tachycardia development, which can lead to a sharp drop in arterial pressure.

Prior to analogues of Mildronat, the following should apply:

• Rozchin Dinaton for injection;
• Bravadin tablets;
• Dibicon in tablet form;
• Gistokhrom at vglyadі razchiny, recognized for іnєktsіy;
• Kudevita in looking capsules;
• Coroxan tablets;
• Trimectal in the form of capsules;
• Ethoxydol tablets;
• Ubinon capsules.

The price of the drug in pharmacies

Find out about the price of Mildronate in 2018 and cheap analogues >>> Variety of the drug Mildronate in different pharmacies can be tested. The price is related to the choice of more cheap components in the preparation and the pricing policy of the pharmacy chain. But it’s important that the difference in price between foreign and Russian counterparts is practically invariable.

How to take "Mildronate"

"Mіldronat" at likuvanni

The drug, with its power, tones the body, excites yoga in toxic speeches and induces the sour needs of clitin. Zavdyaki drug lyudina vytrimuє great vantazhennia and rehabilitating energy reserves. Doctors prescribe to people with diseases of the heart, chronic and crippled brain blood circulation. Also, a prescription is written for reduced use, physical overvoltage, thrombosis of the network, chronic bronchitis, and after surgery for short-term rehabilitation. The drug helps and is ill for alcoholism. A lot of bodybuilders take yoga for zahistu in the heart disease, improving the efficiency of training and improving the eating of m'yaziv.

The drug is released in the form of capsules and is transparent for injections. Zastosuvannya is contraindicated for women, mothers who are aged, with hypertension and intracranial puffiness. Before the victoria "Mildronate" obov'yazkovo should consult with the doctor.

Zastosuvannya "Mildronata"

Mildronat has a powerful effect, so the faces should be taken until evening and bazhano until їzhі. However, when taking drugs, the effectiveness of the drug does not change.

The drug is prescribed in the complex therapy of chronic alcoholics, 0.5 g 4 times a day internally and internally at the same dose 2 times per day. Lіkuvannya prodovzhuyut prodovzh 7-10 days.

Ailments for angina pectoris take capsules with a dose of 250 g 3 times a day for a course of 3-4 days and after a stretch of 1.5 months and a dose of 2 times a day. In case of myocardial infarction and angina pectoris, urticaria is prescribed on the first day one time, then 3 times a day, 250 g internally for 4 days and then twice a day, 3 times a day, 250 g each.

Under the hour of contagion, the sitkivka of the eye “Mildronat” should be introduced for help in the injection, so that the eye can be fought through the lower eye. Assign 10-day likuvannya, 50 g per doba.

In case of acute disorders of blood circulation in the brain, doctors recommend 0.5 g 1 time per doba internally for 10 days. If necessary, therapy is continued for additional capsules 0.5-1 g 1 time per doba.

After strong rosum or physical urges "Mildronat" is taken 0.250 g internally 3-4 times per day for 14 days.

Mildronate is a low-toxic drug, which does not cause any side effects and is not safe for healthy patients.

Korist that Skoda zastosuvannya Mildronate

For athletes and people of a frail age, such a drug, like Mildronat (abo Meldonii), is already well known. However, most of the Russians have become obsessed with the power of the drug only now, in connection with the investigations of low anti-doping agencies, which were in the ZMI. Spontaneously, Mildronate was prescribed to fight heart problems, which are blamed on aphids, energy vitrates, or the body's deterioration. Today, the drug is often taken by healthy people, athletes, and those who want to win the disease.

Yak de Mildronate?

Today, Mildronate is dispensed in three medicinal forms:

• Gelatin capsules of two sizes.
• Rozchin for injections.
• Walkers.

In all speech patterns, the main speech is meldonium. Wine is an analogue of the component that enters the warehouse of the skin cells of the human body. By taking Mildronate to bring before the launch of silent chemical reactions and offensive results:

• Polypshennya working indications in the body, promotion of practice.
• Enhancement of humoral (improved through radini) and tissue immunity.
• Dull reaction of psychological and physiological overexertion.
• Defender of cardioactivity.

For such powers of authority, the drug can be administered to a young, mature, and frail person to improve the symptoms of heart function. Brown medicine for sportsmen, people who are worried about serious physical and emotional pressures.

What is the dosage of the drug?

Therapeutic powers of Mildronate are manifested in the staleness in view of the fact that it is planned to be stagnant.

The main effects, on which it is possible to develop in the course of medical treatment, are:

• In case of heart failure, the strength of the sooner heart matter increases, thus reducing the risk of angina attack, moreover, meldonium increases the resistance of the body to physical stress.
• As if the myocardium has become weaker, the speed of molding of children with signs of necrosis decreases, and, obviously, the period of rehabilitation is shortened. At the same time, the blood circulation of the ear, ischemia, is gradually improved.
• As a person is aware of the development of physical stresses, Mildronate induces the normal supply of sour to the cells, changes the accumulation of toxins in them and the outputs of the cellular metabolism, increases the stability of the cells and their structures, changes the cells supermundane ruination. As a result, the speed of the exchange processes increases, the body becomes stronger.

Zdebіlshkogo vіdguki pro zastosuvannya drug based on meldonium positive. However, the necessary result of therapy is less possible with proper dosing, as it is prescribed individually. Before taking Mildronate, you should undergo an obstezhennja at the cardiologist and wait with him especially for the drug taken.

• Mildronate can tone up the effect on the central autonomic nervous system. Tse often vikoristovuєtsya for the liquidation of the disorder, which vinikli on aphids abstinence syndrome (through chronic alcoholism).
• Zastosovuєtsya drug that in ophthalmology. Vіn priyaє pіdvishchennyu gostroti zor for rahunok positive vplyu on drіbnі sudini, scho sіtkіvku krov'yu.

The maximum virulence of inducing positive effects is within the hour of variation for injections. Building walks show up to 78% yoga efficiency. Regardless of the fact that the form of the faces stagnates, the products of this decay will be brought to light. The stench does not create any toxic urge and do not hurt the organs of vision.

Who needs to take Mildronate?

The drug is contraindicated for children and young adults who have not reached 18 years of age. Having injected meldonium into the body of a woman during the first hour of vagity and lactation until the end of pregnancy, in view of this stasis in the qi period, the next disappearance.

Tablets and capsules of Mildronate are prescribed for such cases:

• ischemic illness at the warehouse of complex therapy;
• disease of the vessels, zocrema of the periphery of the arteries;
• physical, rozumova and emotional overstrain;
• the need to speed up the process of rehabilitation after the transferred operation after a successful recovery;
• heart failure of chronic type;
• chronic pain in the heart due to the presence of obvious pathology;
• obstructive chronic disease (bronchitis, asthma, emphysema) chronic type;
• rehabilitation after a stroke;
• chronic alcohol consumption in complex drinking.

Rozchin for іn'єktsіy mozhe zastosovuvatsya at all resurfacing camps. Krim tsgogo, vin dodatkovo vikoristovuєtsya in such moods:

• hemophthalmos (blood ingestion in the sklopodibne body of the eye) of total, subtotal and partial type;
• bloody near the eye;
• damage to the internal apple, expansion of the vessels from the yogo surface;
• shaping of thrombi, which will cause damage to the passage of vessels as a result of pathological processes in the central ventricle of the sitkivka.

It is not necessary to recognize one of these diagnoses by a profile fakhivtsy, it is not necessary to independently recognize oneself as having received Mildronate in any form. It is necessary to adjust the dosing frequency of taking with the doctor, reconsider, there is no contraindication before carrying out specific therapy.

Meldonium is often prescribed in combination with other medicines to strengthen their therapeutic powers. They are most often accompanied by diuretics, bronchodilators, anticoagulants and antiplatelet agents. In any case, it is necessary to respectfully follow your camp and tell the doctor about any reactions from the side of the body.

Promotion of Mildronate in sports and dietology

Today, more and more often Mildronate is taken by healthy people, but in every case it is necessary to consult a doctor. Athletes - professionals and amateurs - show particular interest in the drug. Your body at some point ceases to cope with physical stress. For the support of yoga strength, medicines with meldonium are ideal.

• Mildronat expands the body's capacity, promotes the progress of yoga displays, increases the results. Value as static, and dynamic activity.
• The effectiveness of sports training is improving, because The drug stimulates the eating of m'yaziv, including heart, brown speech. Who knows the volume that allows you to increase the trivality of approaches.
• Despite the fact that the robot's heart is getting better, Mildronate is not a dope in yoga's direct mind. In light of this, the athlete does not have a lot of weight, it just shows vibrancy, which is necessary for the correct set.
• The energy reserves of the body are replenished richly, sound lower. Tse vіdbuvaєtsya through those scho s kіtin more actively vyvodniyatsya products of metabolism.
• The effectiveness of Mildronate is obvious both in strength training and in cardio exercises, which train virility.

In addition, meldonium often zastosovuyut at the complex of entrances, directing to the order from the vag. At the same time, meldonium was not seen as an independent benefit for losing weight. Speech speeds up the metabolic processes, lowers cholesterol levels, and does not allow the body to actively adhere to physical changes, necessary lowering of the vag. In this rank, the promotion of Mildronate and sport can become optimal for reaching an ideal body.

The right way to take Mildronate

The rules for taking the drug for people and women are the same and understand the peculiarities of the medical care.

• The therapy schedule may be depleted so that Mildronate is taken until 17.00. The components of the warehouse increase the alertness of the body, which can negatively damage the modes of work and recovery.
• With a judicious method, the drug is prescribed at a dose of 500-1000 mg of two per day. Trivality of the course to lie down in the type of pathological state that sounds vitrimuetsya in the range of 12 days or 4-6 days.
• Athletes-amateurs are recommended to take Meldonium 500 mg per dose. Trivality of the course - 2 tyzhn. Let's try to break for 2-3 days and the course is repeated. For professionals, a single dose and the frequency of taking can be increased by 2 times.

It is important to understand that the continued use of Mildronate may cause a decrease in its effectiveness. That is why it is not necessary to chase after quick results, follow the scheme recommended by the doctor.

Side effects of Mildronate

Like in any medical case, preparations based on meldonium may have their own minuses. Before them, you can add a long list of side effects, although the stench rarely manifests itself beyond the rules of the reception.

• Allergy at looking overthrown, in a rush, visipu. Most often it is trapleyaetsya at internal lingual introduction.
• Dyspeptic disorders in the eyeballs, vomiting, burning, nudity, heaviness in the stool.
• Tachycardia on the background of emotional awakening.
• Decreased arterial pressure.

The drug is contraindicated for children under 18 years of age, women and women who are young, and also for people who may:

• Increased sensitivity to the warehouse drug.
• Pathologies of liver and liver up to chronic insufficiency.
• Movement of the intracranial vice, including through the swelling.
• Tricks of an unknown nature.

Mildronate is sold without a prescription. When buying the drug, it is necessary to pay attention to the dosing (250 or 500 mg), so as not to overdose.

How to use "Mildronate" in complex therapy for stroke?

Meldonium (mildronate) is considered to be a group of medicinal products that improve metabolism on the clitin level. Vіn increases the energy capacity in the body, spriyaє efficient utilization of sour.

Meldonium similar to the warehouse with ?-butyrobetaine, which is found in the organisms of healthy skin people. With the development of ischemic processes, the amount of ?-butyrobetaine in the tissues of the nervous system is sharply reduced. Yogo store can be recommended for help to the receptionist Mildronate. With this method of introducing the drug into the body, it does not matter.

The medicinal value is added to the balance between the processes of slowing down and utilizing the sour in the body due to insufficient intake. Meldonium is ahead of the blame for ischemia and fights against the consequences. Also, Mildronate sprays the vibration of active speech, as it affects the walls of the vessels and causes spasm. To this, it is shown to the recognition of likіv є great.

With neurological illnesses, Meldonium may not be appreciated, the stones change the stroke zone and help to revive the next one.

During processes that run chronically, the medical condition improves memory, respect, normalizes the intracranial pressure - increases the efficiency of brain function. Practically daily contraindications before the zastosuvannya tsgo likarskogo sobu.

If you take liquids in capsules or if you look at injections, you can detect the following effects in the body:

• reduced arterial pressure;
• increase in vibrancy and practicality (after physical, mental ambition);
• support of the cardiovascular system (cardiomyocytes, vessel endothelium);
• change in the flow of stress factors and emotional overload;
• stimulation of immune forces - against anti-Russian, anti-bacterial immunity;
• protection of neurons in the infusion of under-oxidized products after severe impairment of cerebral blood flow

Medical forms, diya that confession

Meldonium can be taken from capsules of 250, 500 mg. The package contains gelatin capsules with white powder No. 10.

The main form of release for parenteral administration (intravenous drip, strum) - 10% in ampoules. The package contains 10 ampoules for injection.

Mildronate syrup is available in 100 ml bottles.

When taken orally, the passage of the drug through the intestinal wall is observed. This method of safe exposure to the blood is close to 78% of the introduced speech. Іn'єktsії Mildronate without intermediary in the bloodstream ensures 100% availability for tissues, after which the veins are distributed to all organs.

The internal method of introduction is the most efficient. The conversion of the drug occurs in the parenchyma of the liver, after which the metabolites are removed from the body through a nirk filter. How long does it take to get the stench out of fabrics? The period of sighting is 3.5-6 years.

When do they prescribe a medical bill?

Shown to be recognized as great:

1. Acute stasis - hypertensive encephalopathy, transient ischemic attack, stroke.
2. Prevention of recurrent stroke.
3. Compensated for that decompensated heart failure, cardiomyopathy (toxic, hormonal, hypertrophic, constrictive), which supports therapy for ischemic heart disease. Chi is not prescribed as a first-line drug.
4. Sudine disease of the internal apparatus, dystrophy of various genesis. Indications are indicated for hemorrhage in patients with a sloppy body, sciatica, thrombosis of the central vein.
5. Meldonium zastosovuyut at the complex treatment of alcohol addiction, after the withdrawal syndrome.
6. The promotion of physical reserves to the body of athletes.
7. Increased drowsiness, weakness, depression, disruption of the sleep regimen and insomnia. For such states, the priority may be the oral route of administration of the drug.

How many times to take capsules and rozchin, as well as how to wine, will be discussed below.

In some cases, the drug cannot be taken?

Before the reception of the medical speech, there is a follow-up on the contraindication. Mildronate is a non-invasive drug, about which there are numerous international studies. Regardless of the price, there are a number of stations, for which Meldonium is not assigned:

Having learned the methods of Olga Markovich in the treatment of strokes, as well as the remembrance of my functions, the memory of the relief of constant headaches and the tingling of the heart - we virishi urged yoga and your respect.

• brushes, swellings and other volumes of brain tissue;
• impaired venous circulation, as well as liquorodynamics in an empty skull;
• for up to twelve years (do not prescribe injections and capsules);
• the period of breast growth and vaginess;
• individual intolerance to the components of the drug;
• with low arterial pressure;
• nirkova and liver failure (it contributes to the administration of the drug and increases the pressure on the organs).

Vagіtnіst is included in the contra-indication, but there are no traces of such a contraindication. As a result, the doctor made a decision about the need to inject Mildronate, after which the breast should be taken. Indicated before confession of guilt, revisit the risk of confession of expenses. From 12 to 16 years it is possible to put liquids in the form of syrup.

Features

Let's take a look at the specifics of the drug after a stroke and discuss how much to take. Mildronate can be administered orally and parenterally (intravenously). The maximum additional dose is 1000 mg, as it is a serious indication. Іn'єktsiї it is possible to instill 5 ml 1-2 times a day (method of trival drip infusion on a physiological basis or internally). Vikoristovuvaty trohi more than 10 days, then continue to stop the preparation in capsules.

Skilki and how long to accept faces? Capsules of 250 mg and injections of 10% are prescribed 2 times per day. Terms of likuvannya lie down in the case of illness and can vary from 2 tyzhniv to several months.

For example, as an indication for improving the respect and rozumovykh zdіbnosti, enough for a course of 10 days.

For the treatment of the eyes and adnexal apparatus, parabulbar injections are made. Ampoules of Mildronate should be properly diluted in water for injection. The method of introducing internal contra-indications. It is not recommended to take Meldonium after 5-6 years of the evening, the shards of the wine are awake to the body. The effect of the drug lasts for about 3-4 months.

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Pobichna diya

Side effects develop in case of overdose, as well as in case of impaired excretion of metabolites. From the side of the blood circulation system, the following reactions are cleared up: orthostatic hypotension, decreased arterial pressure, confusion.

With one-hour administration of Mildronate with cardiac glycosides, nitroglycerin, side effects in the body are observed. Also, boredom can appear, the severity of epigastrium (trimaetsya up to 12 years). Vikoristannya vnutrishnyom'yazovo calls out a strong bіl at the place of injection.

In lonely depressions, Meldonium calls out a wild or miserable allergic reaction - shearing shkir, hanging, Quincke's snag. Unsafe life side effects accompany the parenteral method of administration (intravenously).

Relevance of the challenge in neurology

Meldonium helps to promote blood flow and energy processes in gostrih and chronic ailments of the central nervous system. Vіn mає maє vlastіstі zbіlshuvаtі vіdkіstі єєєєє єє є є є є є є іє є є є є є є rіzmіrіv іschemіchnogo fossa.

Vykoristannya likіv in a complex liking of patients with a neurological profile, a short period of rehabilitation, with the normalization of intellectual functions, the development of negative manifestations in the mental sphere. Also, the neurological deficit is changing - coordination of movements, paresis and sensitivity, reflection.

So, as a starting period, it reaches 2 years, by stretching this term, it is possible to accept it. Indications for stosuvannya for the specialty of neurology: the transfer of damage to the cerebral circulation, dyscirculatory encephalopathy, the transfer of neuroinfection.

Achievement in sports medicine

Capsules of the medical specialty help to increase the power to improve the tolerance of physical challenges not only in people who are ill, but also in healthy people.

Since 2016, this drug has been taken by the Anti-Doping Agency, so be it any way to stop professional athletes is unsafe.

Vartist likarskogo zasobu in pharmacies of Moscow and St. Petersburg

Skіlki koshtuє drug, deposit in the form of release. The price of Mildronate in capsules of 250 mg varies in the range of 280 to 300 rubles, 500 mg rubles, 10% in ampoules rubles.

In this article, you can find out about the instructions on how to apply the drug Mildronate. Presented are the opinions of the site - supporters of their faces, as well as the thoughts of the doctors of the fahivtsiv of how Mildronat was won by his practice. Great prohannya actively add your opinions about the drug: they helped or didn’t help people get sick, as they were afraid of aggravating that side effect, which may not have been declared by the doctor in the annotation. Analogues of Mildronate for the presence of obvious structural analogues. Vykoristannya for treatment of heart attacks and strokes and reduction of metabolism in tissues in adults, children, as well as with vaccinia and breastfeeding.

Mildronate- A drug that improves metabolism. Meldonium (speech to the drug Mildronate) is a structural analogue of gamma-butyrobetaine, speech, which is found in the skin cells of the human body.

In the minds of the increased ambition, Mildronate is responsible for the delivery and need of clitin in acid, the accumulation of toxic products in exchange in clitin, protecting them from damage; may also be a tonic infusion. As a result of this stagnation, the organism is gaining viability and viability, and quickly replenishing energy reserves. Zavdyaki tsim authorities Mildronat vicorist for exaltation of various disorders of the heart-vascular system, bleeding of the brain, as well as the promotion of physical and rozumovo pratsezdatnosti.

As a result, a decrease in the concentration of carnitine increased the synthesis of gamma-butyrobetaine, which leads to vasodilatory power. With acute ischemic myocardial damage, Mildronate improves the elimination of the necrotic zone, a short rehabilitation period.

In case of heart failure, the drug increases myocardial sluggishness, increases tolerance to physical distress, reduces the frequency of angina attacks.

In case of acute and chronic ischemic disorders of cerebral hemorrhage, I improve blood circulation in the ischemic socket, apply redistribution of blood to the crust of the ischemic tubercle.

Efficient in case of vascular and dystrophic pathology of the ocular fundus.

The drug reduces the functional impairment of the nervous system, which develops against the background of severe alcohol intake in patients with chronic alcoholism with withdrawal syndrome.

Pharmacokinetics

When I take the drug internally, it is easy to get wet from the SHKT. It is metabolized in organisms to two main metabolites, which are excreted by drugs.

Indication

• in complex therapy of IXC (angina pectoris, myocardial infarction), chronic heart failure, dishormonal cardiomyopathy;
• in complex therapy of gostrih and chronic disorders of cerebral circulation (stroke and cerebrovascular insufficiency);
• reduced practice;
• physical overload (including athletes);
• withdrawal syndrome in chronic alcoholism (in combination with specific therapy for alcoholism);
• hemophthalmos, bloody in a variety of etiologies;
• thrombosis of the central vein of the network and її hilok;
• retinopathy of various etiology (diabetic, hypertensive)

Form release

Capsules 250 mg and 500 mg

Rozchin for internal, internal and external and parabulbar injections (injections in ampoules).

Instructions for stopping and dosing mode

capsules

In case of possible development of a stimulating effect, the drug is recommended to be taken in the first half of the day.

In case of cardiovascular diseases in the warehouse of complex therapy, the drug is administered internally at a dose of 0.5-1 g per doba, the frequency of ingestion is 1-2. Likuvannya course - 4-6 days.

In case of cardialgia on the background of dyshormonal dystrophy of the myocardium, Mildronate is administered internally at 250 mg of 250 mg per doba. Likuvannya course - 12 days.

In case of impaired cerebral blood flow in the acute phase, the drug is administered intravenously (in the upper dosage form - 500 mg 1 time per dob for 10 days), then we switch to taking the drug intravenously at 0.5-1 g per doba. Hot therapy course - 4-6 days.

In case of chronic disorders of cerebral blood flow, the drug is taken internally at a dose of 0.5-1 g per doba. Hot therapy course - 4-6 days. Repeated courses are prescribed individually 2-3 times per day.

In case of rozumovyh and physical addictions, 250 mg intravenously is prescribed 4 times per doba. Likuvannya course - 10-14 days. If necessary, repeat therapy after 2-3 days.

In chronic alcoholism, the drug is administered internally at 500 mg 4 times a day. Likuvannya course - 7-10 days.

Ampoules

In case of cardiovascular diseases in the warehouse of complex therapy, the drug is prescribed at a dose of 0.5-1 g per doba intravenously (5-10 ml for injections with a concentration of 500 mg / 5 ml), the multiplicity of ingestion is 1-2 times per doba. Likuvannya course - 4-6 days.

In case of impaired cerebral blood circulation in the acute phase, the drug is administered intravenously at a dose of 500 mg 1 time per dob for 10 days, then we switch to the intravenous drug (in the upper drug form - 0.5-1 g per dob). Hot therapy course - 4-6 days.

In case of vascular pathology and dystrophic diseases of the system, Mildronate is administered parabulbarally in 0.5 ml intervals for injections at a concentration of 500 mg/5 ml for 10 days.

In case of rozumovyh and physical addictions, intravenously, 500 mg is prescribed 1 time per doba. Likuvannya course - 10-14 days. If necessary, repeat therapy after 2-3 days.

In case of chronic alcoholism, the drug is administered intravenously at a dose of 500 mg of alcoholic beverages per doba. Likuvannya course - 7-10 days.

Pobichna diya

• tachycardia;
• change AT;
• psychomotor arousal;
• head bіl;
• dyspeptic symptoms;
• allergic reactions (blackened shkiri, hanging or hanging, swollen shkiri, swelling);
• Severe weakness;
• sloppy.

Contraindication

• movement of the intracranial vice (incl. in cases of damage to the venous flow, intracranial puffiness);
• childish and juvenile age up to 18 years;
• Increased sensitivity to the drug.

Congestion with vagity and breastfeeding

Safe zastosuvannya Mildronate pіd vagіtnostі not brought. In order to get rid of the possible unacceptable influx on the fetus, the drug did not show signs of pregnancy.

It is not known that the drug is seen in breast milk. If it is necessary to ingest Mildronate during lactation, breastfeeding should be given.

especially vkazіvki

Patients with chronic diseases of the liver and should be careful with a trivial drug. If you need a trial (more than a month) injection of the drug, you should consult with a doctor.

A good report on the treatment of acute myocardial infarction and unstable angina pectoris in cardiological conditions shows that Mildronate is not a first-line drug for acute coronary syndrome.

Whiskers in Pediatrics

In children and adolescents up to 18 years of age, the efficacy and safety of Mildronate in the form of capsules and the range for injections has not been established.

Inflowing into the building to the maintenance of vehicles and control of mechanisms

There is no data about the unfriendly injection of Mildronate on the rapidity of the psychomotor reaction.

Medical interaction

In case of total congestion, Mildronate potentiates antianginal effects, some antihypertensive drugs, cardiac glycosides.

Mildronate can be combined with antianginal drugs, anticoagulants and antiplatelet agents, antiarrhythmic drugs, diuretic drugs, bronchodilators.

In case of total congestion with Mildronate, nitroglycerin, nifedipine, alpha-adrenergic blockers, hypotensive diseases and peripheral vasodilators, the development of mild tachycardia, arterial hypotension (should be taken care of when congested no such combination).

Analogues of the medicinal preparation Mildronate

Structural analogues for fluffy speech:

• 3-(2,2,2-Trimethylhydrazinium) propionate dihydrate;
• Vazomag;
• Idrinol;
• Cardionate;
• Meditern;
• Meldonium;
• Meldonij-Eskom;
• Meldonium dihydrate;
• Melfor;
• Midolat;
• Trimethylhydrazinium propionate dihydrate.

For the presence of analogues of liqivs for intoxicating speech, it is possible to go down to the ailments, for some help, an effective drug, and look at the obvious analogues from the likuvalny ї dії.

Mildronate, which has been widely recognized by Russian athletes for over 30 years, since September 2016 has been raptly squandered to the “harrowed” doping list - it provoked a sharp surge in interest in the drug among other sportsmen.

Why did it all start

At wide stakes, they started talking about Mildronate recently - if the famous Russian tennis player Maria Sharapova made a statement, she knew that in її samples taken after the Australian Open-2016, the drug "Mildronate" was detected.

The sportswoman discovered that she regularly took meldonium for 10 years through health problems - data from the ECG were unstable, and in 2006 she showed signs of diabetes, which had previously been observed in her homeland. I didn’t know anything about doping before.

Mildronate was found in doping tests not only Sharapova, but also many Russian athletes, middle Olympic champions. We threaten to disqualify for the same term.

What do you know about meldonium

The drug was developed at the Latvian Institute of Organic Synthesis in the 1970s, and then developed by the pharmaceutical company Grindex.

Zvuchchay Mildronate is prescribed for the treatment of cardiovascular diseases, such as, for example, stable angina pectoris, chronic heart failure, cardiomyopathy. Vіn recommendations for hospitable and chronic ischemic disorders of the brain hemorrhage, with reduced praxis and perevantazhennia - both physical and emotional.

Athletes take Mildronate to increase vibrancy during training, as well as to adapt the body to neuropsychic challenges during training.

Grindex was told: they have no confirmation of the fact that faces can improve sports results during the boom period. Navpaki, taking meldonium during the period of magic can bring bad luck.

The representative of the pharmaceutical company has indicated that Mildronate recommends taking courses of trials from 4 to 6 days, at the discretion of the doctor, the course can be repeated once a day. The company did not explain what the necessary intake of drugs on a permanent basis for people with symptoms voiced by Sharapova was.

Naskіlki primed fence

The All-World Anti-Doping Agency (WADA), acting against the doping challenge in sports, added meldonium to the list of drugs to be taken from 1 September 2016. Until then, athletes could take yoga legally.

Shows that in Russia Mildronat vicor is more often rich, lower in other lands. Thus, the results of a recent study showed that in 2015, if faces were not yet included in the WADA list, meldonium was known in 17% of samples taken from Russian athletes and less than 2.2% of samples from athletes from other countries.

About the reasons, through yakі mildronat having spent to the “harrowed list”, nothing is known. Juris Bundulis, head of the board of directors of the Grindex company, said that the Agency did not provide arguments to explain the use of the drug.

The drug is not doping, sings at Grindex. The drug improves the process of oxidation of fatty acids, reducing the ability of the body to vicorate as a source of energy. Productivity of healthy cells Mildronate does not increase. Ivar Kalvinsh, the creator of meldonium, explaining that the drug protects the hearts of athletes from the "deadly consequences of work on the borders of the possible", and to improve sports results is not the result of building.

In addition, the company especially emphasized the safety of Mildronate intake - on the basis of recent data from Grindex about any side effects associated with the use of the drug by athletes, nothing is known at the moment.

Mildronate is gaining popularity

In the meantime, Maria Sharapova's statement called out not only a growling discussion with ZMI, but an increase in sales to Mildronat. Anatoly Tenzer, director of development at NVK Katren, spoke out on the surge in the number of Mildronat's percussion requests: “Earlier, the number of inquiries on the site did not exceed 50–60 per day, then on the 8th birch it was 1100, and on the 9th - 1200.” The increase in drinking wine was promptly caused by a doping scandal and a rise in the interest of people to the drug from the "hindered list".

Growing up in sales. For the data of the site analysts, the increase in sales of another day of birch in the same region with the first one is 1023%. The numbers speak for themselves.

Growing interest in meldonium was recorded in Russia. Following the cob "History of Mildronate", the price of the drug on the site rupharma.com, which hopes to be able to buy faces that are either sold on the territory of Russia, with delivery all over the world, was 22 dollars. At a time, a package of 40 capsules of 250 mg costs 39 dollars, and the delivery of Mildronate can only be done in advance, so that you can put it on the list for the delivery of drugs.

Virobnik - the Grindex company, at its discretion, hangs out in adversity with the decisions of WADA. I plan to submit all the necessary evidence for the inclusion of mildronate from the “black list” in 2017. There is every chance that disqualified athletes, including Maria Sharapova, turn to the future of the advancing fate and rejoice us with new achievements.

Xenia Skripnik

Photo thinkstockphotos.com

Meldonium mildronate was created in the 70s of the last century by the researcher of the Latvian Institute of Organic Synthesis - Professor Ivan Kalvinsh. Tse is a synthetic analogue of y-butyrobetaine, which is respected by the picture. Speech improves the passage of active fatty acids through the cellular membranes and prevents the accumulation of non-oxidized fatty acids in them.

On the back of the tongue, the drug was patented as a growth stimulant for domestic birds and creatures. Over the years, mildronate began to actively vicorate for the exuberance of the people: as an exhausting metabolic zasib, and after another hour - in sports - for the encouragement of athletes.

The main task of mildronate is the stimulation of metabolic processes in the body and the activation of glycolase. The drug reduces the amount of carnitine, which vibrates the body, which expands the judgment. Allows you to improve the work of the heart, increasing the speed of the myocardium. Tim himself will increase the physical potential of a person and the building of a building will have a significant impact.

Carnitine is one of the natural derivatives of vitamin B, which is synthesized by the human body in a small amount. Taking part in the transport of fatty acids, ensuring the functionality of the m'yazovo tissue of the brain.

With the correct application of the original product, it is possible to increase the clitinic immunity, reduce the overstress (both physical and psycho-emotional). According to the results of the 2015 World Anti-Doping Agency, the All-World Anti-Doping Agency showed that the promotion of mildronate in sports allows to increase the performance of athletes, to speed up their promotion during the period of improvement, to improve the virility of that camp nervous system.

Pharmacodynamics

The drug is dispensed in capsules, syrup, tablets and ampoules for intravenous and intravenous administration. The rest of the presentation is like a transparent iris (clear ampoules of 5 ml). Capsules - hard gelatin 250 mg. If I take the drug internally, it will be well absorbed from the SHKT. Already for a couple of years, yoga has a maximum concentration in the blood.

Meldonium may have an agonizing metabolic effect, creating a balance of delivery and slowing down sour to the body, activating the exchange of speech in an anaerobic way (that is, without the participation of sour).

In this way, speech is created by a significant world to promote the healing and regeneration functions of the body, to activate tissue immunity.

In case of oral administration of vikoristan, the bioavailability of the drug was about 78%. Internal administration gives 100% bioavailability. The maximum concentration of the drug in the blood is seen already in a couple of years, and the period of drinking becomes close to 6 years.

Features

Due to a wide range of pharmacological effects, the drug zastosovuyut in the treatment of diseases.

Indications for acceptance

Fahivtsі prescribe the administration of mildronate in such cases:

• Heart pathologies of the ischemic type (heart failure, heart attack, cardialgia);
• Pathology of the organs of the dichal system, associated with insufficient intake of acid (for example, bronchial asthma);
• Damage to cerebral circulation; brain stroke;
• Damaged blood circulation in the eyes;
• Deyakі form diabetes;
• Dovgotrivali іtelektualnі navantazhennya, nervovy vysnazhennya;
• Trivaly physical adventure;
• Withdrawal syndrome in chronic alcoholism (in combination with the main therapy).

Zastosuvannya in sports

How can you zastosovuvaty mildronat amateurs and chi go wine for professionals? Absolutely, yes. This is an ideal synthetic replacement for gamma-butyrobetaine. Meldonium allows you to significantly increase the vibrancy of an athlete, the shards change the level of fatty acids, which are victorious in energy. The stench itself is most often vicorated by the body in times of intense physical urge. І fatty acids are transformed into energy in the cells of the heart meat. In this rank, the heart is working for the enforced regime.

The main task of mildronate is to “reset” the body to generate energy not with the heart, but with sour and glucose. Tim himself is reduced to an interest in the life of important organs, the heart is in front of us. How do I use the drug for an athlete:

• Shvidke renewal with a significant effort - the products of decay are excreted from the body at an accelerated pace, and the renewal of body tissues takes significantly less than an hour. Tse allows you to train more in parts and more productive. The use of the drug is more relevant for any kind of sport and bodybuilding among them. Moreover, mildronate will show itself equally effective in cardio training, as well as in significant strength efforts.
• Increased use of the drug increases the virility of the athlete, significantly increasing the speed of his reaction. Tse bezporednya vіdbivaєtsya on the speed, spritnostі, significantly increase the level of strength, obviously, you can significantly increase the vanity.
• Accelerated delivery of glucose to the cells of the body is a miraculous prevention of the development of low heart pathologies and important disorders in the robotic heart for a heart attack. Mildronate to protect the "motor" against the development of arrhythmias, angina pectoris and other disorders.
• The blunting of the negative reaction to the change (may be affected by the impact as a physical reaction, as well as the nerve overstress) is a similar effect, especially relevant for athletes during the period of passage of light and dry hour - the drug is superimposed on the body, if the wine is taken on between physical abilities.
• Polypshenya will become with asthenia - the correct course of the drug will help to overcome weakness, sleepiness and prevent the development of chronic automy syndrome. All this will help to improve the performance of any kind of sport and bodybuilding in that number.

Important! Bulo b pardon vvazhat, scho building mildronat vplinut on the growth of m'yazovoї masi. Ale wine gives the body the necessary charge of energy, helps to change, gives the opportunity to increase physical strengths, like, at one’s own pace, to help achieve the desired result.

How to take Mildronate?

The method of dosing the drug is to lie down before the name of the drug, for which it is taken. So, with diseases of the heart, zocrema, angina pectoris, the course may become 1-1.5 months. The additional dose for the first 3 days is 0.75 g, divided into three doses. Then the frequency of taking is reduced to 2 times per day (after dosing is overdone by ourselves - 0.75 g, divided into 3 doses).

In case of bronchial asthma, the trivality of rejoicing becomes 21 days. Additional dose - 0.25 g per dose. Take mildronate with bronchodilator drugs.

In case of pathologies of the internal fundus and dystrophic changes in the 10% dose, the drug is administered subconjunctivally and retrobulbarly, 0.5 ml each, for 10 days. In case of a strong ignition process in the heart, the course is supplemented with the introduction of corticosteroid locally.

Important! The method of administration of the drug, the dose and duration of the course are prescribed exclusively by the drug in an individual order, depending on the health characteristics of the body and the main indication for the drug.

In sports, mildronat can be taken at any time you look. Obviously, the best result can be achieved by taking the course of the drug by injection. True, in this case, it is necessary to take the dosage more seriously and mothers of the beginners of the injection of medications. Lovers better choose their own pills or capsules.

Important! In case of oral administration, the drug should be taken at the daily hour, balm 30 minutes before or after. Mildronate cannot be taken as a drink: the drug should be taken as a whole, washed down with a significant amount of water.

To improve performance in sports, an additional dose of meldonium is recommended to be 500 mg (250 mg twice a day). In order to precisely rozrahuvat dosing, follow the rozrahuvat 15-20 mg per kg of vaga. At the day of training, the drug is taken for five years before the cob, but not later than 5 years in the evening, shards can be brought to a nervous overexcitation.

Medical interaction

Antianginal drugs - increase blood flow to the heart. Anticoagulants - reduce blood pharynx. Antiaggregants - prevent platelet adhesion at the stage of blood formation. Vasodilators - reduce blood pressure. Glycosides can cause antiarrhythmic disease.

For those who want to take mildronate as a complex course, we will not hesitate to recognize it in interaction with other drugs, and especially in the case of sing-alongs. Shards of meldonium change the reduction of energy by the body from the heart to glucose, with victoria at once from a diet without carbohydrates, the result can be far from improving. Mildronate is especially relevant in itself when it comes to eating carbohydrates and kisen. In this rank, it’s wonderful to show yourself when doing gymnastics, big, pushing strength training, looking out for vibrancy, football, tennis and other.

One-hour congestion with antiarrhythmic and antianginal diseases, diuretics, anticoagulants, bronchodilators and others is allowed.

For the sake of caution, vicoristovate mildronate in combination with vasodilators and hypotensive medications. A similar combination can cause tachycardia and increased arterial pressure.

Є th series of preparations, which will be significantly used in different speeches, which are examined. Tse - heart glycosides and coronary dilating diseases.

Side effects and contraindications

As a rule, the drug is well tolerated, but in some cases a negative reaction to the body is possible:

• From the side of the shlunkovo-intestinal tract - dyspeptic problems;
• From the side of the cardiovascular system - arterial striations, tachycardia;
• From the side of the immune system - hanging that black on the skin, sverbіzh, angioedema thinly;
• From the side of the central nervous system - nerve overexcitation;
• Severe weakness.

In times of overdose, a number of symptoms can occur: headache, weakness, decreased arterial pressure, confusion, and so on.

For the sake of protection, take metabolic precautions in chronic nirk and hepatic ailments.

Mildronate zastosuvannya in such cases:

• with vaginess and during lactation;
• individuals who have not reached 18 years of age;
• with a high intracranial vice;
• in cases of individual intolerance to the components of the drug.

Why is mildronate used for doping?

In 2016, the roci drug was not used up to the point of medical speeches, taken for the purpose of sports, and doping is taken into account. Nutrition about those for whom mildronate is needed, praises no less than professionals from the great sport, and quiet, who sees the gym on the amateur level.

Many doctors do not know why doping was recognized as a metabolic problem. Aje yoga brilliance is a reminder of the functionality of the body, and not an advancement of yoga physical indicators. For those who plan to fight with mildronate exclusively on the amateur level, VIN is absolutely fearless: on the contrary, VIN stimulates the increase in the intensity of training and the increase in their effectiveness.