About retribution for sex. Impaired speech exchange and hormone balance in people

One of the functions of the liver is the exchange of hormones. Not much to remember in case of acute processes, but to take a turn in case of chronic illnesses, in the first place in case of cirrhosis of the liver. Zocrema, which disrupts the metabolism of state hormones, is injected into the development of such symptoms,

like plemista, erythema of the dorsum, gynecomastia in people, as well as sudinny zirochki (telangiectasia).

Impaired metabolism of hormones can prevent the development of the ascitic-ascitic syndrome.

The liver pours in the concentration of hormones on the periphery, less in the world - the very synthesis of these biologically active speeches.

Adrenaline is one of the main catecholamines, hormones in the cerebral ball of the epithelium. The production of this hormone is closely related to the synthesis of two other speeches of this group - norepinephrine and dopamine. Syrovine for the synthesis of all three catecholamines, phenylalanine and tyrosine. Norepinephrine is prestaged by octopamine, adrenaline is prestaged by dioxyphenylalanine.

Norepinephrine is the main mediator of the sympathetic nervous system. A close role is played by dopamine. Adrenaline and nor adrenaline serve as the main presorptive agents of the vascular system.

On the cob of the 1970s, the theory of toxic neurotransmitters is believed to be in the fact that, with overworld intake of tyrosine and phenylalanine in the upper bloodstream, there is a risk of a greater increase in toxic products in their metabolism, thus reducing octopus amine and norepinephrine from synapses of nerve cells, disorganizing the work of disrupting the communication and development of Komi.

On the cob of the 1980s, a sharp increase in adrenaline and norepinephrine in the blood of ailments was shown, which is found in the liver-clitiny coma. There is still no satisfactory explanation of this phenomenon. You can only assume that the increase in neurotransmitters causing the need to increase the concentration of norepinephrine and adrenaline.

Aldosterone is the main mineralocorticoid. For dukuєtsya glomerular ball of measles supranirkovyh zaloz. Stimulation of sodium reabsorption by the tubules of niro from the primary section. In the process of reabsorption, potassium ions are destroyed from the section. About 0.2 mg of the hormone is synthesized per doba in the glomerular ball of the supra-nervous folds.

The liver produces angiotensin-I, which, reacting with renin, metabolizes angiotensin-P. Angiotensin-11 plays the role of one of the stimulants in the production of aldosterone in the adrenal cortex.

The liver plays an important role in the inactivation of aldosterone. In case of severe illness (cirosis, alcoholic gostrium), this function is lost. Obviously, at the same time, there is an induction of enzymes that convert the hormone, and blame the mind for the development of secondary hyperaldosteronism. Dosі not tsіlkom zrozumіlі in vzaєmini aldosterone and natriyuric hormone in the heart (div. Water-salt exchange).

State hormones. The liver takes part in the exchange of estrogen and androgen. The role of the estrogen shift is especially great.

In case of chronic insufficiency of liver function in people, their own syndromes, gynecomastia, state of impotence are blamed. In the period of acute severe liver disease, the concentration of highly active female hormones (estradiol, estrone) increases in blood sirovats and decreases - inactive ones (estriol).

In cases of mild liver disease in people, there is a slow increase in the concentration of testosterone and progesterone in the blood, in severe cases (active with ascites) - a significant decrease in the level of testosterone and progesterone.

Serotonin is a non-vasoactive hormone, which is produced by clitins distributed throughout the body. One of the precursors of serotonin is tryptophan. Hormone imperceptibly interferes with the speed of transmission of nerve impulses. To date, the remaining fates have been reported about the increase in the amount of serotonin on aphids, a sharp increase in the concentration of tryptophan in the blood serum of patients with liver-clitin and portal-hepatic insufficiency. Hyperserotoninemia on a certain increase in the concentration of such amino acids, such as tryptophan, and the concentration of tyrosine and phenylalanine, which often rises at the same time, contributes to the development and progression of comi in patients with cirrhosis of the liver.

The health of the liver and serotonin is well seen from the clinical features of various localizations of carcinoids. As if there were still rotting in the intestines, or a subshrub ulcer, a flash syndrome during the day, at that hour, with carcinoid legenia, purple hyperemia of the upper veins of the tuba, often with an exanthema of the type of kropivyanka, it was pronounced.

Hormones of the thyroid gland. The amount of triiodothyronine in the blood serum decreases in case of severe acute and chronic (especially alcoholic) diseases of the liver.

Insulin - div. carbohydrate exchange.

Glucagon - div. carbohydrate exchange.

Gastrin. It is secreted by G-clitins of the antral cavity of the stomach, small intestine, subductal cavity and other. Period navіvrozpadu 10-40 min. Up to 90% of gastrin is inactivated by the liver. Direct studies did not show a regular and significant increase in the concentration of the hormone in the blood sputum of patients with virus disease, including those due to hepatogenic viruses.

Spilno z G. M. Gerasimov mi (1985) showed a significant increase in the place of gastrin in some ailments in the terminal phase of liver failure. It is also noted that the development of encephalopathy on aphids of high hypergastrinemia is important in patients with severe liver diseases.

Histamine is a physiologically active speech from the group of biogenic amines. The significant world is inactivated by the liver. It is allowed that hypergistaminemia, which is observed in a number of ailments with severe liver diseases, may play a significant role in the development of hepatogenic gastroduodenal virulence.

Hormonal balance is the key to mental health, and yoga is easy to destroy. Skin people have to go through natural periods of hormone levels - the stage of maturation and menopause, but also other depressions, if the hormones in the body enter the necessary balance. For example, you can be viklikane with a plethora of toxins, or the wrong way of living with insufficient sleep, or filthy eating, sickness of the thyroid gland, or diabetes. So, otherwise, it is important to understand what is the cause of the imbalance in order to know the best ways to solve the problem. Traditionally, sing of hormonal preparations - protizaplidnyh pills, injections of insulin and others. Prote ta kuvannya is accompanied by immeasurable minuses and side effects. A person can develop staleness, the result of which will be brought to the end of life to live in the faces, less sticking with problems. Hormonal preparations smooth out the symptoms, but do not help the sickness. Until then, the stench increases the risk of heart attack, osteoporosis, depressive state, and the absence of cancerous puffs. Might as well be an alternative! Luckily, there are no harmless ways to naturally turn the hormonal balance. Nasampered, varto is assigned to the symptoms and the causes of the disorder, and then you can take up the pleasures, as if not accompanied by any side effects, as in the case of the most popular medicines.

Signs of hormonal imbalance

Symptoms can be different, fallow in the type of illness, with which you have stumbled. Prote є deyakі zagalnі znaki, raznoy miroy characteristic more ailments. They include problems of the reproductive system and disruption of the menstrual cycle, depressive disorder and apparent anxiety, chronic exhaustion, sleeplessness, reduced potency, change in appetite, problems with etching, loss of hair and increased vigor.

Widespread causes of hormonal disorders

As a result, you have encountered problems with sleep, with colic and changes in appetite, increased stress and increased metabolism, perhaps, on the right at the supramental level of estrogen. Like yoga, now, too little, there are obvious signs, such as a decrease in libido, reproductive problems, menstrual irregularities and unstable moods. Hypothyroidism is caused by a set of vagi, chronic fatigue, herbal problems and an irregular cycle. Decrease in testosterone is manifested through erectile dysfunction, the consumption of m'azovoy masi, zavisu vag, chronically in that mood. Hyperthyroidism lead to stress, use hair on that vag, disruption of sleep and arrhythmias. Diabetes is caused by a set of vagi, nervous disorders, worsening of the morning, chronic fatigue, aggravated respiratory problems and dermatological problems. Injection of adrenaline can lead to nausea, pain in the medulla, depression, sleep disturbance and concentration, problems with the reproductive system.

What causes illness, what disrupts the hormonal balance?

Different factors, as well as their combination, can lead to rehab more sickness. The middle of the widest range of varto call problems with poisoning and food allergies, zayva vaga, frying processes that call out to filthy eating and a sedentary way of life, genetic health, injection of pesticides, chemical speeches, nicotine and alcohol, as well as an increase in the level of stress in patients with insufficient intake . Would you like to neutralize the impact of such factors on your body? Speed ​​up in natural ways!

Live in the roots of fat

The body needs a wide variety of fats, including the amount and amount of cholesterol. Fats help to produce hormones, which reduce inflammation and stimulate metabolism, which helps in the consumption of vagi. The ideal sources of brown fats are coconut oil and avocado. Include them in the diet once a day, so that you can remember the positive changes in the shortest term.

Vikoristovyte korisnі herbs

Specially grown plants, called adaptogens, help the body to restore hormonal balance and resist chronic diseases. Acting like this, the growth helps to overcome the problems of the thyroid gland, cause depression and reduce the level of adrenaline. Sea buckthorn, ginger, lemongrass, eleutherococcus and others can be seen up to similar growths. Take the necessary precautions for your sickness, and regularly instill yoga in the form of tea or medicinal drops.

Change the pickling system

Turbine about etching is the key to health, but it has recently been brought to light that problems in the herbal tract can lead to autoimmune diseases, for example, arthritis or damage to the thyroid gland. Antibiotics, high carbohydrates and dietary carbohydrates, eating with an insufficient amount of cellular tissue, toxins, chronic stress and chronic ignition processes can cause damage to etching. Try to eat as balanced as possible, so that you can get rid of many problems with your health and with a good look.

Don't beat up cosmetic products for the body

A lot of creams for the body vikoristovuyutsya shkіdlivі khіmіchnі speechovina, for example, parabens. Dolіdzhuyte warehouse zasob_v before їх vzhivannâm і choose і, yakі vengeance natural efirnі olії, olіyu coconut, shea abo ricinov.

Exercise regularly

Exercise does not help to improve a good physical shape, but also to strengthen the heart-vascular system, speed up metabolism and help people to become healthy. How to remember fahivtsі, the most effective is regular cardio training.

Sleep more and surround the stress

Well, it’s easier to say it, lower it, it’s really necessary to control the sleepiness of sleep. The rіven cortisol, the stress hormone decreases at the same time during the night. Lyudina, as she can’t hang out, is constantly vigilant, and there, in her quarters, she can suffer from serious hormonal disorders. In this way, a simple stabilization of the order and a triple night's sleep can become the causes of a decrease in stress.

Change of caffeine and alcohol

Caffeine is depleted in the body for a few years, pouring into the central nervous system, speeding up the heartbeat, raising the concentration and vibrating hormones like the brain vibrates. In times of hormonal problems, such an influx of bagan is turned off.

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Just as an integral indicator of the level of carbohydrate metabolism in a living organism is the concentration of glucose in the blood, then a similar indicator of the intensity of fat metabolism is the concentration of NEFA. At the beginning of the calm, the average becomes 500-600 µmol / 100 ml of plasma. This parameter lies in the spontaneity of lipolysis and liposynthesis in adipose tissue and liver, on the one hand, and the release of free fatty acids as a source of energy in m'yazah and other tissues - s іnshoy.

Carbohydrates are utilized and mobilized in the body more easily and equally, lower triglycerides. Therefore, the level of glucose in the blood is more stable, the concentration of NEFA is lower. If the concentration of glucose in the blood is ± 30%, then the concentration of essential fatty acids in certain situations (starvation, intense m'azova stress, severe stress) can increase up to 500% (Newsholm, Start, 1973).

Such a significant increase in the level of NEFA in the blood is explained by the fact that the severity of the reaction of lipolysis sharply outweighs the severity of the reaction of the utilization of NEFA. I want NEFAs to be utilized in more advanced tissues, lower glucose or other monosaccharides, stinks are readily available for oxidation in functional tissues and therefore, in a number of physiological situations, the most important and most important energy them with dzherelami for rich types of clitin, zocrema skeletal mucus, in case of lack of glucose .

In the myocardium, NEZHK is a smutty product for any brains. On vіdmіnu vіd monosaccharides shvidkіst spozhivannja fatty acids in all tissues to lie in vіd їhnої concentration in the blood and not to lie in the permeability to them clitin membranes (Іton, Steinberg, 1961).

Regulators of lipolysis and liposynthesis serve mainly as hormones, as they take part in the regulation of carbohydrate metabolism. In case of hormones that stimulate hyperglycemia, they are hyperlipacidemic, at the same time as insulin, which leads to hypoglycemia, it will prevent the development of hyperlipacidemia. In addition, ACTH, lipotropin and MSG are involved in the regulation of fat metabolism in vertebral deacons, which may cause hyperlipacidemic disease (Fig. 99).


Mal. 99. Multihormonal regulation of lipolysis and liposynthesis:


Insulin is the only hormonal stimulator of lipogenesis and lipolysis inhibitor. Stimulation of liposynthesis by the hormone in adipose tissue, as well as in the liver, is responsible for the strengthening of the metabolism and utilization of glucose (divine more). Galvanization and lipolysis may be due to activation of cAMP phosphodiesterase by insulin, a decrease in the concentration of cyclic nucleotide, a decrease in the level of phosphorylation of inactive lipase and a change in the concentration of the active form of the enzyme - lipase a (Korbin et al., 1970). Cream of this, lipolysis in adipose tissue under the influence of insulin is affected by galvanic hydrolysis of triglyceride in products of increased glycolyse hormone.

Glucagon, adrenaline, growth hormone (in fetuses also CSM), glucocorticoids, ACTH and other hormones are lipolytic stimulants in fatty tissue and liver. Glucagon and adrenaline realize their hyperlipacidemic effects by additionally activating adenylyl cyclase and enhancing cAMP conversion, which promotes additional cAMP-depleted PC, converting lipase to activated lipase a (Royuzon ta in., 1971). Perhaps, in a similar way, they act on lipolysis of ACTH, lepotropin and MSH, growth hormone (or yogo lipolytic fragment) and glucocorticoids, as well as CSM, help lipolysis, imovirno, stimulating the synthesis of protein enzymes on equal transcription and translation tsії (Fane, 97).

The latent period of the increase in the level of NEFA in the blood under the infusion of glucagon and adrenaline becomes 10-20 minutes, under the infusion of GH and corticosteroids - 1 year or more. The next thing to guess is that ACTH may have a folding effect on lipid metabolism. Influence on adipose tissue indirectly and through stimulation of the production of glucocorticoids by the cortex of the epidermis, being, moreover, a prohormone of a-MSH and a sraktor, which stimulates the secretion of insulin (Beloff-Chain and in, 1976). The lipolytic effect may also be Tz and T4.

Hormonal stimulation of lipolysis in the adipose tissue of the liver in the mind, starvation and further stress hyperlipacidemia lead not only to the promotion of oxidation of NEFA, but also to the galvanization of the utilization of carbohydrates in meats and, possibly, others fabrics. Tim himself glucose "saves" for the brain, which is more important to utilize in carbohydrates, not fatty acids. In addition, significant stimulation of lipolysis in adipose tissue by hormones promotes the release of ketone bodies from fatty acids in the liver. Rest and overdose of acetooctate and hydroxybutyric acids can be substrates for brain indigestion (Hawkins et al., 1971).

The second integral indicator of lipid metabolism is lipoproteins (LP) of different thickness, which transport cholesterol and other lipids from the liver to other tissues and tissues (Brown, Goldstein, 1977-1985). LP of low strength is atherogenic (which indicates atherosclerosis), LP of high strength is anti-atherogenic. The biosynthesis of cholesterol in the liver and the metabolism of various LPs are regulated by Tz, glucocorticoids and state hormones. With T3, that estrogen contributes to the development of atherosclerosis of the vessels.

The adaptive role of hormones, which regulate the intermediary metabolism, and short information about yogo endocrine pathology.

The secretion of a complex of hormones, which regulate carbohydrate and fat metabolism, should be deposited according to the needs of the body in energy resources. In case of starvation, mucosal and nervous stress, as well as other forms of stress, if the need for carbohydrates and fats increases, a healthy organism experiences an increase in the level of secretion of these hormones, which promotes the mobilization of such remodeled reserve forms of living speech and caused hyperglycemia and hyperlipacidemia ( Fig. 1). 100).

At the same time, the secretion of insulin begins to churn (Khusey, 1963; Foa, 1964, 1972). First, at the same time, it stimulates the secretion of insulin more importantly, which stimulates the synthesis of glycogen in the liver and meats, triglycerides in adipose tissue and liver, as well as protein in other tissues.



Figure 100. The role of hormones in the regulation and self-regulation of intermediate carbohydrate and lipid metabolism:
the strong arrows indicate stimulation, the alternate parts indicate galmuvannya


Signals that stimulate the secretion of insulin, an increase in the concentration of glucose, fatty acids and amino acids that are absorbed into the blood, as well as an increase in the secretion of hormones in the mucosal-intestinal tract - secretin and pancreosimin. In whom the secretion of hormones "mobilization" is galvanized. However, GH, present in small concentrations in the blood at the stages of taking it, injects glucose and amino acids into the fat tissue, and adrenaline - in the m'angular tissue. At the same time, a low concentration of insulin during starvation and stress, stimulating the entry of glucose into the ointment, eases the effect of hyperglycemic hormones on the ointment tissue.

One of the main signals that modulate the secretion of insulin, glucagon, adrenaline and other hormones that take part in the adaptive self-regulation of the intermediate exchange of carbohydrates, as it was intended, is the level of glucose in the blood.

The increase in the concentration of glucose in the blood stimulates the secretion of insulin and galmuic secretion of glucagon and other hyperglycemic hormones (Foa, 1964, 1972; Randle, Hales, 1972). It has been shown that the effect of glucose on the secretory activity of α-ta/5-layers of the submucosal lining, as well as chromaffin cells, is a significant result of the direct interaction of hexoses with specific receptors of the membranes of the inner cells.

At the same time, the effects of glucose on the secretion of other hormones are realized only on the hypothalamic and/or temporal cerebellum. Similar to glucose on the subscapular fold and the cerebral ball of the supraclavicular folds, but not on the cephalic calendula, they can probably work and fatty acids, ensuring self-regulation of fat metabolism. A number of factors of self-regulation of the secretion of visceral hormones can infuse a lot of internal and external stress agents into the rest.

With deep damage to carbohydrate and fat metabolism, a person has been diagnosed with the most common endocrine disease - blood diabetes. One of the natural conditions for diabetes is the injury of other great vessels that change their minds in ailments to the development of atherosclerosis and other vessel damage. In this way, diabetes will increase the number of cases, as if they are suffering from heart disease.

It was said that the development of circulatory diabetes is primarily due to the absolute lack of insulin. At this time, it is important to consider that the basis of the pathogenesis of diabetes is based on impaired regulation of insulin regulation and, perhaps, a number of other hormones on the tissue, after which in the body the cause is absolute or deficient in insulin, which is try with an absolute or appreciable excess of glucagon or other "diabetogenic" hormones (Unter, 1975).

Imbalance of dihormones can be caused gradually to the development of persistent hyperglycemia (circulation concentration in the blood is 130 mg%), glucosuria and polyuria. The remaining two symptoms gave the name of the disease - cirrhosis of the cervix, or cirrhosis of diabetes. In the minds of the carbohydrate intake (glucose tolerance test), the glycemic curve in sick people is changed: after taking 50 g of glucose, internal hyperglycemia in sick people is equal to the norm stretched in the hour and reaches great values.

In a row with the impaired utilization and deposition of carbohydrates in diabetes, there is an increase in fat metabolism: increased lipolysis, galvanic lipogenesis, increased NEFA in the blood, increased oxidation in the liver, accumulation ketone bodies. Increased illumination of ketone bodies (ketosis) leads to a decrease in blood pH - acidosis, which plays an important role in the development of illness (Renold and others, 1961).

Ketoacidosis to lie, evenly, more often in the development of damage to the vessels (micro- and macroangiopathies). In addition, ketoacidosis underlies one of the most important complications of diabetes - diabetic Komi. With an arc of high blood volume (800-1200 mg%), another coma may develop. It is to blame for the significant loss of blood flow and osmotic pressure of blood while maintaining normal pH (hyperosmolar coma).

As a result of trivalent and various disturbances in carbohydrate, fat and protein metabolism, which are accompanied by disturbances in the water-salt balance, various micro- and macroangiopathies develop in sick people, rock (nephropathy), nervous system (neuropathy), trophic virazki. shkira, deep atherosclerosis, mental disorders.

It has been established that diabetes mellitus is a polypathogenetic disease. It may be associated with: primary deficiency of insulin secretion and hypersecretion of diabetogenic hormones (insulin sensitive, or juvenile, form diabetes); sharply reduced sensitivity of tissue targets to insulin (insulin-resistant forms, or diabetes, dangerous). In the pathogenesis of the first form of ailment, which causes 15-20% of ailments to develop diabetes, a significant role can be played by the fall-off factor and the conversion of autoantibodies to proteins of the island apparatus. In the development of another form of illness (over 80% of cases, as if they suffer from diabetes), there is a significant amount of excess intake of carbohydrates, obesity, and a poor way of life.

To compensate for circulatory diabetes, it is necessary to replace the therapy with various drugs and insulin; low-carbohydrate (low-fat) diet and sucrose-lowering synthetic preparations - sulfanyl sechovin and big guanide. Apparently, insulin is less effective in insulin-sensitive forms of illness. In addition, we are trying to create a "piece-of-the-art subslut worm" - a compact electronic-mechanical device charged with insulin and glucagon, which, when connected to the bloodstream, can stimulate hormones in the fallowing concentration of glucose to the blood.

Symptoms of circulatory diabetes may be due to other illnesses that are not primarily related to the endocrine functions of the submucosa or to insulin and glucagon deficiency (various forms of hypercorticism, acromegaly).

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It is not easy to show that our vaga is not celery that chicken fillet on the steam, but like invisible chemical speeches in the midst of us. And let the hormones themselves give the body a command to accumulate fat or to get rid of yoga.

website- for exact knowledge about everything in the world, especially as this knowledge helps us to become beautiful and healthy.

A lot of chinnikiv are poured into the vaga: low-volatility, recession, overdose, stress, and in addition, hormones play a role, yak they show metabolism (exchange of speech).

The hormones themselves virishyuyut, accumulate chi spit fat.

insulin

Clitini possess energy from glucose. As soon as the rіven of glucose rises, and the rіvіnková zadіl see іnsulіn. Wine helps to deliver glucose to the clitin. Figuratively seemingly, at the same time from glucose, insulin knocks at the door of the room. Clitini can smell a thud and work, giving glucose to go inside.

Insulin gives us energy, but it also accumulates and saves fat. Like in the body high rіven insulin, fat is deposited.

Cortisol

Cortisol is the stress hormone. Wines are seen as napkins to prevent the fall of glucose in the blood. The very same stress calls for a meal, especially for licorice - so the body accumulates strength to withstand difficult situations.

Cortisol reduces the speed of speech exchange, to save energy. As the body has a high level of cortisol, fat is stored.

Leptin

Leptin is the same hormone of production, which is vibrated by fatty cells and sends a signal “Vy Sity” to the brain. In the control of the speed of the exchange of speech and the violation of the work with fat: choose to burn. Like in the body a low level of leptin, you will pass the time. Often, before the fall of leptin, it is important to get married to sleep, so it is important to correctly vibudovuvat the daily routine.

Thyroid hormones

Thyroid hormones (T3 and T4) are vibrated by the thyroid gland and are activators of fat breakdown. Vіd them to deposit swidkіst exchange of speeches. As there is a low level of thyroid hormones in the body, fat is deposited.

What is it necessary to eat and how to exercise in order to lose weight?

life

Dosledzhennya show that the frequency of eating is optimal - all the same, 3 times a day.

Zhorstki diet - stress for the body. You will become stringy, but not for long, and the body will reject the signal that important hours have come, it is necessary to work on the stash for a black day. As a result, it’s still not rich, you can get bigger.

Rather lose weight properly, dorimuyuchis small calorie deficit (for example, with your norm 1 900 kcal, you get 1 700 - the exact amount is covered in the fall due to your age, height, and way of life). So you change the body so that the supply of fat is not needed.

Take the product, as it is the least possible to sip on the production of insulin. These products have a low glycemic index (GI). It shows what level of glucose will be in the blood after the introduction of this drug.

Instead of high carbohydrates, protein and cellular tissue: the stench is good and help not to overdo it. Protein is the main material for everyday life of m'yaziv, and the more m'yaziv, the more calories stained the body to instill peace in the camp.

right

If we exercise, the m'yazi will increase the supply of glucose and require additional replenishment. The study showed that the most effective increase in sensitivity to insulin is high-intensity interval training.

The optimal hour to take is 1-1.5 years for the death of advances. І stitch 20 quills, like going about high-intensity interval training. After such training, the body continues to drink more calories. Take a carbohydrate-protein (or carbohydrate) drink with you for training - to help trim cortisol under control.