What is a cytological smear? cytology. Cytology analysis of the cervix. Cytology as a science

A skin woman with an ear of severe life should regularly see a gynecologist and have a smear for cytology. Manipulation from smear collection is carried out by the doctor during the preventive examination on the gynecological chair. Once tested for cytology, it is possible to examine the mucous membrane of the epithelium and cervix, to detect inflammation, cancer and oncological diseases of the female cervix.

The difficulty of diagnosing gynecological pathologies often leads to the wasting of an hour, which would have been possible to obtain effective treatment. Sometimes oncology develops asymptomatically, and the cause of illness can only be identified through special investigation. Cytology smear analysis makes it possible to detect cancer at an early stage and promptly initiate treatment.

What does a smear on flora and cytology reveal? Its main significance lies in the detected pathological changes in tissues, which can later turn into cancerous tissue. If a smear for cytology of the cervix is ​​given regularly, then negative signs can be detected at an early stage - for example, an incendiary type of illness, which can be cured in the short term with similar therapy and avoid further complications. kladnennyam.

What does a smear for cytology indicate? The results of the investigation can be either positive or negative.

Positive can be “bad”, “pathological”, “atypical” or mean “dysplasia”. It is clear that a bad smear on cytology is not the norm, but in the mucous membrane there is a change in the ignition type, the smear reveals atypical pathological cells, which are not to blame.

A negative smear is considered normal. This means that the cervix is ​​healthy, the cellular structure of the epithelium is not changed, and the microflora does not contain pathogenic bacteria. When submitting a smear for cytology, the decision is made by a gynecologist. Fahivtsi are kindly requested to make inquiries at least twice per river.

Indications and contraindications

If you need a smear for cytology:

  • when diagnosed;
  • at;
  • Sometimes, for example, an atrophic type of cytology smear will indicate hormonal changes in the body during menopause that has arrived;
  • how to vikorist;
  • with genital herpes;
  • for obesity;
  • once the human papilloma virus has been detected in the body;
  • at times, as a woman lives in a hopeless state of life;
  • during preparation before production.

Do not wait too long to carry out this investigation as soon as possible.

Do not take a smear for cytology:

  • at the hour of menstruation, so red blood cells may be detected on a cytology smear;
  • during an acute ignition process in the state sphere;
  • with clear visions of the oil, pronounced verbine.

Vaginism may be contraindicated before the procedure. Women, since they cannot live a normal life (maidens), have no sense of going through investigations. Women who have undergone surgery to remove the uterus - hysterectomy - complain.

How to take a smear

How to take a smear for cytology, tell all the women who have undergone this procedure more than once. The doctor or midwife will take a smear during an hour of examination on the gynecological chair.

Before completing the procedure, the doctor should administer a gynecological speculum. After visually examining the cervix, take a sterile brush and lightly scrape the epithelium from the surface of the cervix and cervical canal, as well as from the urethra. The biological material is removed and applied to a microscope and sent directly to the laboratory for further processing.

How long does it take to get a smear for cytology? The results of the investigation will become visible in 1 day.

To obtain reliable results, it is important to prepare in advance of the smear procedure:

  • stay away from intimate fluids for 24-48 years before seeing a gynecologist;
  • turn off various vaginal products - mastila, sprays, suppositories, etc.;
  • do not urinate before taking a smear for 2 years.

Decoding the results

Deciphering a smear for cytology makes it possible to obtain information about the level of purity of the product and the presence of pathologies in a woman.

There are 4 levels of purity:

  • First step. It rarely occurs. The smear reveals only rod flora, a small amount of squamous epithelium and isolated leukocytes.
  • The step is different. The expansion is the result of research into what happens among healthy women. The flora in the cytology smear contains squamous epithelium, coca and other non-pathogenic microorganisms.
  • Stage three. This stage of purity means the beginning stage of the ignition process. The detected inflammation in the smear for cytology prompts the beginning of other diagnostic investigations to find the root cause of the problem. The smear contains polymorphic rod flora, neutrophilic leukocytes, granulocytes and striated epithelium, in addition, the results of cytology of a smear from the cervical canal may reveal yeast fungi with a tendency to multiply and actively sti.
  • Step four. The ignition process of turns is bright. The cocoa and bacillary-cocae flora are important. This research result will require a term search for the cause of the infection and similar treatment.

Doctors often talk about the fifth stage of purity, the result of which is a precursor to the oncological process in a woman’s area, because in which a large number of atypical cells are revealed in the smear.

Smear at the hour of pregnancy

A smear for cytology in case of pregnancy is done at least 3 times - this can be done either in the gynecologist’s office or in a private laboratory - for example, the Invitro method of single cytology. The research is important for monitoring the soil microflora in the expectant mother. If there is the slightest suspicion of infection in the women's condition, cytological investigations are carried out additionally.

The result of a smear on the flora of the 2nd type of purity with vaginity means an ignition process in the state ways of a woman. At this stage, your mother may experience itching in the area of ​​the external organs, as well as a change in the smell and color of vaginal areas. It is necessary to cleanse thoroughly and up to the canopy in order to minimize infection of the membranes and the fetus.

Cytological research is one of the most popular in oncology. With this help, the doctor evaluates the state of the cellular elements and learns about the evil and benign nature of the new creation. The peculiarities of the human body, the tissue storage of organs, tissues, and other parts of the human body are considered. Cytological investigation is used in the diagnosis of pre-cancerous diseases and malignant neoplasms of various organs: cervix and uterine body, mammary gland, thyroid gland, leg, skin, soft tissues and cysts, scholum ovo-intestinal tract, lymphatic nodes, etc. For cytological examination, take the cervix, sputum, excrement, excudation, etc.

When is cytological examination indicated?

Most doctors - therapists, gynecologists, oncologists and other physicians - go to cytological diagnosis if they suspect a pulmonary illness.

The cytological method is used to trace new growths in various organs - the skin, mammary gland, legion, mediastinum, liver, cervical organs, thyroid gland, anterior mammary gland, testicle, ovaries, lymphatic organs. and knots, algae, vines, soft fabrics, brushes ta in. .

The greatest expansion of cytological investigations occurred in gynecological patients. This is a simple screening method that has proven its effectiveness in diagnosing precancerous and early cervical cancer.

There are several cases where cytological investigations help to detect cancer of the vulva, lung, michura, etc. at early stages, if radiographic and endoscopic examinations did not reveal changes.

During the period of treatment of swelling, it is necessary to continuously monitor the effectiveness of the therapy being carried out. For whom are effective diagnostic methods necessary? Cytological investigation in these cases allows us to quickly remove the need for more nutrition, which is caused by doctors, leading to the progression of the disease. Cytological examination is also widely used after completion of specialized (surgical, chemotherapy or metabolic) treatment to control the progression of illness and early detection of possible relapse or progression of swelling and (examination of lymphatic nodes, pleural exudate, etc.).

The main reasons for cytological investigations in oncology:

  • Screening, preventive examinations
  • Diagnostics – establishing and clarifying the diagnosis
  • Monitoring results immediately and after therapy

What is the significance of cytology versus histological examination?

The importance of cytological examination versus histological examination primarily lies in the fact that the cells themselves are examined, and not through tissues. For histological examination, either surgical material or material collection by trephine biopsy is required. For cytological examination, add a smear from the mucous membrane, scraping from the surface of the swelling or material removed with a fine needle.

Preparation of a histological specimen will require more time than preparation for cytological analysis.

How does cytological investigation follow up?

For analysis, a variety of biomaterials are used.

Exfoliative material for possession using the “listening” method:

  • scraping from the surface of erosions, wounds, wounds;
  • scraping from the cervix and cervical canal, aspirate from the empty uterus;
  • secretions, excretion, phlegm, transudation, exudation, washing water, etc.
  • Follow-up study on atypical cells

Puncture material:

  • punctate, cut off with a thin head (fine head biopsy)
  • trephine biopsy material from pulp and various new products

Operating material:

  • smears and scrapers from the removed tissue, rub, smear and so on. material removed during surgical handing.

Endoscopic material:

  • material removed during endoscopic examination


Cytological examination is the most gentle diagnostic method. The collection of material for analysis proceeds painlessly, in outpatient settings, without traumatic damage to organs and tissues.

The tissue material taken for analysis from the cytology laboratory is transferred to a slide, barked and observed under a microscope.

The cytomorphologist in his work examines the totality of signs of cellular atypia, critically assessing their severity and stage of virulence. The result of the analysis must depend on the professionalism of the researcher who conducts the investigation: both in preparation of the material and in part of the investigation under a microscope.

On the surface of the plump cells there are special proteins - antigens. Moreover, skin plumpness expresses its moisture set of antigens. If you use additional special reagents for immunocytochemical follow-up, the doctor-cytologist can not only determine the presence of malignantly transformed cells in the studied specimen, but also determine the histotype of the swelling, and ї organ affiliation, predictive factors and sensitivity to treatment.


Advantages of the cytological method:

  • absolutely no cost for the patient
  • painlessness
  • Possibility of stagnation of richase cytological studies
  • fluidity
  • diagnosis of malignant tumors at any localization and at any stage of the process.

Ensure that the investigation is carried out for as many years as necessary. Intraoperative cytological examination can be extended over 10 days.

Due to its inconsistency, the cytological method is indispensable for assessing the dynamics of morphological changes in swollen cells during the hour of treatment, to determine the therapeutic effect of treatment. For such patients, there are clear advantages over other, invasive methods of investigation.

Cytological research methods are gradually being refined. The development of endoscopic technology allows for the direct extraction of material for investigation from internal organs that were previously inaccessible for morphological analysis without prompt delivery.

Thus, cytological research, which is highly informative, inexpensive for the patient and fast, due to the absence of tissue injury, is of great importance in oncology.

It will never be possible to diagnose diseases of the organs in women. Especially when it comes to the cob stages of the disease. As a result, valuable hours are wasted, which are necessary for a successful celebration. The development of oncology in most cases is asymptomatic. It is impossible to find out about the presence of cancer without special treatment. One of the methods that can reliably detect the development of cancer cells in the early stages is cytology analysis.

What should be confirmed by gynecological investigation?

Cytology in gynecology is one of the ways to study cellular material. The gynecologist takes a smear from the cervix and cervical canal to identify or exclude pathological cells and dysplasia.

The most important investigation in gynecology is the analysis of a smear from the cervical canal.

The test is carried out under a microscope and makes it possible to quickly recognize atypical cells, showing their shape, size and place of growth.

When decrypted, the test indicates the number of cells in the epithelium of the cell phone. The classification of results is most often followed by the Papanicolaou method. To be insured, the client has a pectonic core. Cervical fabric changes using the standard method are divided into several types:

Stages 2, 3, 4 of changes may indicate the presence of certain illnesses, and itself:

  • vaginitis;
  • genital herpes;
  • candidiasis;
  • papillomavirus.

It is necessary to understand that the investigation shows obvious signs of inflammation, infection conditions, and therefore indicates the cause.

Analysis results

A qualified medical practitioner can decipher the test. Information found on the Internet is obviously inaccurate.

How to compare the result of the analysis:

In addition, it is necessary to remember the special features of cytology investigation:

  1. The test is reliable in 90% of cases. Therefore, this can be carried out for rik chi two. Repeating the procedure is necessary to completely turn off the risk of illness.
  2. 2% of all strokes are uninformative due to the lack of additional research materials.
  3. It is not too late to reveal pathological changes in a smear to talk about the presence of cancer.
  4. Women cannot make a residual diagnosis based solely on a Pap test.

Deciphering the results may involve different techniques. Regular gynecology is instructed to use the Pap test using other interpretation options, for example, the Bethesda system.

Cytology considers the result to be normal if there are daily changes in the cell material. Healthy cells must meet the same standards in shape and size.

In addition, the analysis of a healthy woman can lead to the following benefits:

  1. The uterine cervix is ​​composed of a single-spherical cylindrical epithelium. Rich spherical epithelium is permissible with a smear from the skin.
  2. No pathological changes were detected in the globular epithelium.
  3. The number of leukocytes is taken from 15 units.

Sometimes the results indicate the presence of good cellular material. The situation is not considered normal, but does not lead to severe anxiety due to oncology.

Indications before the procedure and preparation before it


Indications prior to histology analysis include obesity and diabetes. Women who are over 40 years of age are advised to undergo examination at least once per year.

To ensure maximum reliability of the result, before going to the gynecologist, you must complete the following boxes:

  1. It is advisable to take local infusion preparations, for example, a suppository and linseed tampons.
  2. Do not stop the procedure during menstruation, as well as during sudden illnesses due to strong secretions. The smear should be removed only after getting dressed again.
  3. Do not go to the toilet for several years before taking the material.
  4. 2 days before the analysis, you should get rid of formal life.
  5. Don't be shy about douching.

These are simple rules for allowing repeated visits to the gynecologist. Taking a smear takes more than 15 minutes at a time under the supervision of a gynecologist. The procedure goes like this:


The reaction of biological material and barnyard allows us to develop information about the possibility of developing oncological disease. If the test was carried out successfully, it took 7-8 days to apply the material. The woman can learn about the results of the test from the doctor two days after the procedure. If the analysis is carried out as a cito, then the indicators will be known within a few days.

Cytology is a diagnostic method that allows you to detect blood cells and reveal the presence of atypical elements, which indicate the development of illness. In gynecology, cytology analysis has an expanded procedure.

The popularity of the method is easy to explain:

  • First of all, a diagnostic smear for cytology will not require a lot of money;
  • in other words, a guarantee of reliable results in an extremely short period;
  • thirdly, it helps to forestall the development of pre-cancerous and cancerous conditions.

Cytology, smear for cytology and oncocytology - these are popular synonyms of the medical term - Pap test.

Analysis for follow-up of cells in gynecology

The cervical canal or cervix is ​​the anatomical site for collecting cellular material for gynecological examination. This anatomical section functions with two types of epithelium:

  1. rich spherical epithelium (covers the area of ​​the vaginal part);
  2. cylindrical epithelium (runs the cervical canal in the area of ​​the cervix and uterus).

In accordance with physiological norms, cellular elements are regularly renewed. Taking a smear for cytology from these parts of the cervical canal helps to identify atypical cancer cells at the embryonic stage of development.

A cytology analysis will ensure the detection of ovarian changes in the cervical canal of the uterus, which prevents the development of cancer over a period of time. Looking at this reason, a cytology test is an obstetric prophylactic method in gynecology.

Massive smear tests in women, which span across different age groups of the population, demonstrate positive dynamics with a decrease in the incidence of cervical cancer.

If your arch is scheduled for a smear for cytology, don’t give in to panic! This does not mean that you have cancer, but it is a disease of the body. In general, a regular preventive examination and a final smear for cytology reduces the possibility of developing sickness.

Women under 65 years of age should regularly see a gynecologist and cancel all benefits. After 65 years, the frequency of submitting material for cytology is determined individually by the doctor.

A Pap test was performed in the following conditions:

  • To all girls/women who have passed the 18th century. And here the analysis is carried out without medical assistance, for free;
  • The presence of a stately life;
  • Women over 30 years old in the obstructive medical order for goiters are required to take a test once a day;
  • Vagitni. Cytology follows the rules 3 times during the period of fetal vinification;
  • Interruptions in the menstrual cycle, the presence of the human papilloma virus and malignant tumors in close family members are the reasons for performing a smear for skin cytology.

Factors that lead to gynecological illness and a negative cytology test result:

  • Take nicotine;
  • Lack of vitamins A, Z;
  • Immunodeficiency conditions, not including HIV;
  • Infection with chlamydial and herpes infections;
  • The ignition centers of the woman’s state organs are constantly leaking;
  • Sighting of the human papillomavirus in the blood;
  • Systematic intake of hormonal anti-inflammatory drugs;
  • The beginning of a stately life before the 16th century;
  • regular change of state partners;
  • There is a history of several canopies.

Stages of preparation before the analysis

It is important to know what to prescribe when you leave your office. If you are planning to undergo regular preventive examination by a gynecologist and undergo a number of necessary tests, follow these simple recommendations:

  • Forget about nightly pleasures for a few days;
  • Place all chemicals for intimate hygiene on a distant screen and douche;
  • Do not use smears, such as vaginal suppositories, sprays, etc. before performing a smear.

A smear for cytological examination is taken during the initial gynecological examination with speculum. The complexity of all procedures, including inspection, is 15 minutes.

First, the doctor evaluates the walls of the groin and the visible part of the uterus after introducing a gynecological “mirror”. After this, the gynecologist proceeds immediately to collect the epithelium of the cervical canal. For this you will need a probe, a special swab or a brush. Although the procedure is unpleasant and unacceptable, try to relax, otherwise the discomfort will increase due to muscle tension.

The scraps should be removed and sent to the laboratory for further testing. More accurate results from the laboratory will be available in 1-2 days.

The results will indicate either "positive" or "negative". It is completely clear that the decoding includes the item “negative” - this means absolutely healthy cervix, the absence of atypical cells.

The point “positive” is not a clinical diagnosis! So, such a result indicates the presence of atypical cells, but it does not mean at all that the stench will soon become cancerous or they will not. Analysis with a positive result occurs in case of infectious illnesses caused by a disease, and in cases of inflammation.

Decryption additionally includes the stages of the identified process:

  • Stage 1 - the cytological picture has not changed;
  • Stage 2 – minor recovery from the norm, development of inflammation;
  • Stage 3 - single cells with anomalies of the cell elements (incredibly malignant in nature);
  • Stage 4 – solitary cells, including those of a malicious nature;
  • Stage 5 – malignant cells in large bones (exact diagnosis – cancer).

In case of a positive result, regardless of the stage, additional investigations will be considered, such as repeat cytology analysis in case of doubtful results, or colposcopy.

Zagalny stan after taking the material for cytology

There is no need to worry if, within 5 days of taking the smear, brownish-green visions appear. This is a normal reaction of the body that requires treatment. In such a day, there is no need for gynecologists to take special care of hygiene.

To eliminate pain and discomfort, take a break from regular life.

In order to contact the doctor, if after taking the material for analysis, the body temperature increased, sharp pain appeared in the lower abdomen and bleeding.